C
Christine Baechlein
Researcher at University of Veterinary Medicine Vienna
Publications - 25
Citations - 754
Christine Baechlein is an academic researcher from University of Veterinary Medicine Vienna. The author has contributed to research in topics: Hepatitis E virus & Medicine. The author has an hindex of 10, co-authored 19 publications receiving 624 citations.
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Journal ArticleDOI
Hepatitis E virus infection as a cause of graft hepatitis in liver transplant recipients
Sven Pischke,Pothakamuri Venkata Suneetha,Christine Baechlein,Hannelore Barg-Hock,Albert Heim,Nassim Kamar,Jerome Schlue,Christian P. Strassburg,Frank Lehner,R. Raupach,Birgit Bremer,Peter Magerstedt,Markus Cornberg,Frauke Seehusen,Wolfgang Baumgaertner,Juergen Klempnauer,Jacques Izopet,Michael P. Manns,Beatrice Grummer,Heiner Wedemeyer +19 more
TL;DR: The prevalence of HEV infection in Central European liver transplant recipients is low; however, chronic hepatitis E may occur and needs to be considered in the differential diagnosis of graft hepatitis.
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Presence of atypical porcine pestivirus (APPV) genomes in newborn piglets correlates with congenital tremor
Alexander Postel,Florian Hansmann,Christine Baechlein,Nicole Fischer,Malik Alawi,Adam Grundhoff,Sarah Derking,Jörg Tenhündfeld,Vanessa M. Pfankuche,Vanessa Herder,Wolfgang Baumgärtner,Michael Wendt,Paul Becher +12 more
TL;DR: The results of this study strongly suggest that the presence of APPV genomes in newborn piglets correlates with CT, while no association with clinical disease could be observed in viremic adult pigs.
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Identification of a Novel Hepacivirus in Domestic Cattle from Germany
Christine Baechlein,Nicole Fischer,Adam Grundhoff,Malik Alawi,Malik Alawi,Daniela Indenbirken,Alexander Postel,Anna Lena Baron,Jennifer Offinger,Kathrin Becker,Andreas Beineke,Juergen Rehage,Paul Becher +12 more
TL;DR: Interestingly, quantitative RT-PCR from different organs and tissues, together with the presence of an miR-122 binding site in the viral genome, strongly suggests a liver tropism for bovine hepacivirus, making this novel virus a promising animal model for HCV infections in humans.
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Highly divergent hepaciviruses from African cattle
Victor M. Corman,Adam Grundhoff,Christine Baechlein,Nicole Fischer,Anatoly P. Gmyl,Robert Wollny,Dickson Dei,Daniel Ritz,Tabea Binger,Ernest Adankwah,Kwadwo Sarfo Marfo,Lawrence Annison,A. P. Annan,Yaw Adu-Sarkodie,Samuel Oppong,Paul Becher,Christian Drosten,Jan Felix Drexler +17 more
TL;DR: African cattle was investigated and previously unknown HVs at high prevalence and viral loads were discovered, suggesting an influence of the human-modified ecology of peridomestic animals on virus diversity.
Journal ArticleDOI
Prevalence of Hepatitis E virus-specific antibodies in sera of German domestic pigs estimated by using different assays.
Christine Baechlein,Anika Schielke,Reimar Johne,Rainer G. Ulrich,Wolfgang Baumgaertner,Beatrice Grummer +5 more
TL;DR: Though the present study revealed a high seroprevalence of HEV in the German domestic pig population and a potential risk of transmission to humans, the differing results of the tests highlight the necessity of a standardization of serological assays for comparative serop revalence and longitudinal studies.