Christoph Gerber

TL;DR: The basic principles, advantages and limitations of the most common AFM bioimaging modes are reviewed, including the popular contact and dynamic modes, as well as recently developed modes such as multiparametric, molecular recognition, multifrequency and high-speed imaging.

TL;DR: It is shown that cantilever arrays can be used to investigate the thermodynamics of biomolecular interactions mechanically, and it is found that the specificity of the reaction on a cantilevers is consistent with solution data.

TL;DR: In this article, surface stress changes and kinetics were measured in situ during the self-assembly of alkanethiols on gold by means of a micromechanical sensor.

TL;DR: The potential of combining AFM with complementary techniques, including optical microscopy and spectroscopy of mechanosensitive fluorescent constructs, super-resolution microscopy, the patch clamp technique and the use of microstructured and fluidic devices to characterize the 3D distribution of mechanical responses within biological systems and to track their morphology and functional state as discussed by the authors.

TL;DR: In this article, a review demonstrates that STM effectively tests new types of control over the microscopic structure of self-assembled monolayers on gold that should prove useful to their application.