Toshio Ando

TL;DR: In this paper, a high-speed scanner, free of resonant vibrations up to 60 kHz, small cantilevers with high resonance frequencies (450-650 kHz) and small spring constants (150-280 pN/nm), and several electronic devices of wide bandwidth are presented.

TL;DR: This work directly visualize myosin V molecules walking along actin tracks, using high-speed atomic force microscopy, providing corroborative ‘visual evidence’ for previously speculated or demonstrated molecular behaviours, and reveals more detailed behaviours of the molecules, leading to a comprehensive understanding of the motor mechanism.

TL;DR: The basic principles, advantages and limitations of the most common AFM bioimaging modes are reviewed, including the popular contact and dynamic modes, as well as recently developed modes such as multiparametric, molecular recognition, multifrequency and high-speed imaging.

TL;DR: The real-time visualization of crystalline cellulose degradation by individual cellulase enzymes through use of an advanced version of high-speed atomic force microscopy is reported here.

TL;DR: The atomic force microscope (AFM) has a unique capability of allowing the high-resolution imaging of biological samples on substratum surfaces in physiological solutions, which has enabled the direct visualization of dynamic structural changes and dynamic interactions occurring in individual biological macromolecules, which is not possible with other techniques as discussed by the authors.