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Christopher J. Oliphant
Researcher at Laboratory of Molecular Biology
Publications - 3
Citations - 830
Christopher J. Oliphant is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: Innate lymphoid cell & Interleukin 33. The author has an hindex of 3, co-authored 3 publications receiving 711 citations.
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Journal ArticleDOI
MHCII-Mediated Dialog between Group 2 Innate Lymphoid Cells and CD4+ T Cells Potentiates Type 2 Immunity and Promotes Parasitic Helminth Expulsion
Christopher J. Oliphant,You Yi Hwang,Jennifer A. Walker,Maryam Salimi,See Heng Wong,James M. Brewer,Alexandros Englezakis,Jillian L. Barlow,Emily Hams,Seth T. Scanlon,Graham S. Ogg,Padraic G. Fallon,Padraic G. Fallon,Andrew N J McKenzie +13 more
TL;DR: During transition to adaptive T cell-mediated immunity, the ILC2 and T cell crosstalk contributes to their mutual maintenance, expansion and cytokine production and identifies a previously unappreciated pathway in the regulation of type-2 immunity.
Journal ArticleDOI
Bcl11b is essential for group 2 innate lymphoid cell development
Jennifer A. Walker,Christopher J. Oliphant,Alexandros Englezakis,Yong Yu,Simon Clare,Hans Reimer Rodewald,Gabrielle T. Belz,Pentao Liu,Padraic G. Fallon,Andrew N. J. McKenzie +9 more
TL;DR: Mice deficient in Bcl11b exhibit a lack of ILC2 development and an expansion of RORγt+ ILC3s and are unable to clear Nippostrongylus brasiliensis worm infection, but can clear Citrobacter rodentium.
Journal ArticleDOI
Spontaneous atopic dermatitis is mediated by innate immunity, with the secondary lung inflammation of the atopic march requiring adaptive immunity
Sean P. Saunders,Tara Moran,Tara Moran,Achilleas Floudas,Achilleas Floudas,Felicity A. Wurlod,Felicity A. Wurlod,Agnieszka Kaszlikowska,Agnieszka Kaszlikowska,Maryam Salimi,Emma M. Quinn,Christopher J. Oliphant,Gabriel Núñez,Ross McManus,Emily Hams,Emily Hams,Alan D. Irvine,Andrew N. J. McKenzie,Graham S. Ogg,Padraic G. Fallon,Padraic G. Fallon +20 more
TL;DR: In conclusion, this study provides new insights into the understanding of the atopic march, with innate immunity initiating dermatitis and the adaptive immunity required for subsequent development of compromised lung function.