C
Colleen Corcoran
Researcher at Harvard University
Publications - 33
Citations - 4728
Colleen Corcoran is an academic researcher from Harvard University. The author has contributed to research in topics: Wasting & Wasting Syndrome. The author has an hindex of 29, co-authored 33 publications receiving 4661 citations. Previous affiliations of Colleen Corcoran include Brigham and Women's Hospital.
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Journal ArticleDOI
Comprehensive Epitope Analysis of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T-Cell Responses Directed against the Entire Expressed HIV-1 Genome Demonstrate Broadly Directed Responses, but No Correlation to Viral Load
Marylyn M. Addo,Xu G. Yu,Almas Rathod,Daniel E. Cohen,Robert L. Eldridge,Daryld Strick,Mary N. Johnston,Colleen Corcoran,Alysse G. Wurcel,Cecily A. Fitzpatrick,Margaret E. Feeney,William Rodriguez,Nesli Basgoz,Rika Draenert,David Stone,Christian Brander,Philip J. R. Goulder,Philip J. R. Goulder,Eric S. Rosenberg,Marcus Altfeld,Bruce D. Walker +20 more
TL;DR: The data suggest that the impact of T-cell responses on control of viral replication cannot be explained by the mere quantification of the magnitude and breadth of the CD8+-T-cell response, even if a comprehensive pan-genome screening approach is applied.
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Metabolic Abnormalities and Cardiovascular Disease Risk Factors in Adults with Human Immunodeficiency Virus Infection and Lipodystrophy
Colleen Hadigan,James B. Meigs,Colleen Corcoran,Petra Rietschel,Sarah Piecuch,Nesli Basgoz,Benjamin T. Davis,Paul E. Sax,Takara L. Stanley,Peter W.F. Wilson,Ralph B. D'Agostino,Steven K. Grinspoon +11 more
TL;DR: HIV-infected patients with lipodystrophy demonstrated significantly increased waist-to-hip ratios, fasting insulin levels, and diastolic blood pressure compared with controls, demonstrating a metabolic syndrome characterized by profound insulin resistance and hyperlipidemia.
Journal ArticleDOI
Metformin in the treatment of HIV lipodystrophy syndrome: A randomized controlled trial.
Colleen Hadigan,Colleen Corcoran,Nesli Basgoz,Benjamin T. Davis,Paul E. Sax,Steven K. Grinspoon +5 more
TL;DR: This study suggests that a relatively low dosage of metformin reduces insulin resistance and related cardiovascular risk parameters in HIV-infected patients with lipodystrophy.
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Assessment of growth hormone dynamics in human immunodeficiency virus-related lipodystrophy.
Petra Rietschel,Colleen Hadigan,Colleen Corcoran,Takara L. Stanley,Gregory Neubauer,Joseph M. Gertner,Steven K. Grinspoon +6 more
TL;DR: Pulse analysis demonstrated decreased baseline GH in the LIPO subjects but no significant difference in pulse frequency and insulin-like growth factor-I was not different between the groups and the mean GH concentration was correlated inversely with mean GH concentrations in the HIV-infected patients.
Journal ArticleDOI
Effects of Androgen Administration in Men with the AIDS Wasting Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial
Steven K. Grinspoon,Colleen Corcoran,Hasan Askari,David A. Schoenfeld,Lisa Wolf,Belton A. Burrows,Mark Walsh,Douglas Hayden,Kristin Parlman,Ellen J. Anderson,Nesli Basgoz,Anne Klibanski +11 more
TL;DR: In this article, the effects of physiologic testosterone administration on body composition, exercise functional capacity, and quality of life in androgen-deficient men with the AIDS wasting syndrome were investigated.