S
Steven K. Grinspoon
Researcher at Harvard University
Publications - 414
Citations - 30664
Steven K. Grinspoon is an academic researcher from Harvard University. The author has contributed to research in topics: Population & Insulin resistance. The author has an hindex of 90, co-authored 378 publications receiving 28050 citations. Previous affiliations of Steven K. Grinspoon include Boston Medical Center & Columbia University.
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Increased acute myocardial infarction rates and cardiovascular risk factors among patients with human immunodeficiency virus disease.
TL;DR: AMI rates and cardiovascular risk factors were increased in HIV compared with non-HIV patients, particularly among women, and cardiac risk modification strategies are important for the long-term care of HIV patients.
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Adipose-derived circulating miRNAs regulate gene expression in other tissues
Thomas Thomou,Marcelo A. Mori,Jonathan M. Dreyfuss,Jonathan M. Dreyfuss,Masahiro Konishi,Masaji Sakaguchi,Christian Wolfrum,Tata Nageswara Rao,Tata Nageswara Rao,Jonathon N. Winnay,Ruben Garcia-Martin,Steven K. Grinspoon,Phillip Gorden,C. Ronald Kahn +13 more
TL;DR: Transplantation of both white and brown adipose tissue—brown especially—into ADicerKO mice restores the level of numerous circulating miRNAs that are associated with an improvement in glucose tolerance and a reduction in hepatic Fgf21 mRNA and circulating FGF21.
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Cardiovascular risk and body-fat abnormalities in HIV-infected adults.
Steven K. Grinspoon,Andrew Carr +1 more
TL;DR: Progress in understanding the pathogenetic mechanisms and treatment strategies for addressing cardiovascular risk in adults infected with the human immunodeficiency virus are discussed.
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Metabolic Abnormalities and Cardiovascular Disease Risk Factors in Adults with Human Immunodeficiency Virus Infection and Lipodystrophy
Colleen Hadigan,James B. Meigs,Colleen Corcoran,Petra Rietschel,Sarah Piecuch,Nesli Basgoz,Benjamin T. Davis,Paul E. Sax,Takara L. Stanley,Peter W.F. Wilson,Ralph B. D'Agostino,Steven K. Grinspoon +11 more
TL;DR: HIV-infected patients with lipodystrophy demonstrated significantly increased waist-to-hip ratios, fasting insulin levels, and diastolic blood pressure compared with controls, demonstrating a metabolic syndrome characterized by profound insulin resistance and hyperlipidemia.
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Long-term mortality after transsphenoidal surgery and adjunctive therapy for acromegaly
Brooke Swearingen,Fred G. Barker,Laurence Katznelson,Beverly M. K. Biller,Steven K. Grinspoon,Anne Klibanski,N. Nicole Moayeri,Peter McL. Black,Nicholas T. Zervas +8 more
TL;DR: A retrospective review of patients who underwent transsphenoidal surgery at Massachusetts General Hospital between 1978 and 1996 suggests that the decreased survival previously reported to be associated with acromegaly can be normalized by successful surgical and adjunctive therapy.