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Conor J. Meehan
Researcher at University of Bradford
Publications - 89
Citations - 3380
Conor J. Meehan is an academic researcher from University of Bradford. The author has contributed to research in topics: Population & Mycobacterium tuberculosis. The author has an hindex of 22, co-authored 82 publications receiving 2290 citations. Previous affiliations of Conor J. Meehan include Halifax & Dalhousie University.
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Journal ArticleDOI
A Phylogenomic View of Ecological Specialization in the Lachnospiraceae, a Family of Digestive Tract-Associated Bacteria
Conor J. Meehan,Robert G. Beiko +1 more
TL;DR: Analysis of the genomes of 30 Lachnospiraceae isolates demonstrates that adaptation to an ecological niche and acquisition of defining functional roles within a microbiome can arise through a combination of both habitat-specific gene loss and LGT.
Journal ArticleDOI
Microbial shifts in the aging mouse gut
Morgan G. I. Langille,Conor J. Meehan,Conor J. Meehan,Jeremy E. Koenig,Akhilesh S. Dhanani,Robert A. Rose,Susan E. Howlett,Robert G. Beiko +7 more
TL;DR: Differences in functions related to host nutrition and drug pharmacology vary in an age-dependent manner, suggesting that the availability and timing of essential functions may differ significantly with age and frailty.
Journal ArticleDOI
Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues.
Conor J. Meehan,Galo A. Goig,Thomas Kohl,Lennert Verboven,Anzaan Dippenaar,Matthew Ezewudo,Maha R. Farhat,Jennifer L. Guthrie,Kris Laukens,Paolo Miotto,Boatema Ofori-Anyinam,Viola Dreyer,Philip Supply,Anita Suresh,Christian Utpatel,Dick van Soolingen,Yang Zhou,Philip Ashton,Daniela Brites,Daniela Brites,Andrea M. Cabibbe,Bouke C. de Jong,Margaretha de Vos,Fabrizio Menardo,Fabrizio Menardo,Sebastien Gagneux,Sebastien Gagneux,Qian Gao,Tim H. Heupink,Qingyun Liu,Chloé Loiseau,Chloé Loiseau,Leen Rigouts,Timothy C. Rodwell,Elisa Tagliani,Timothy M Walker,Robin M. Warren,Yanlin Zhao,Matteo Zignol,Marco Schito,Jennifer L. Gardy,Daniela Maria Cirillo,Stefan Niemann,Iñaki Comas,Annelies Van Rie +44 more
TL;DR: The current landscape of WGS pipelines and applications, and best practices for M.tuberculosis WGS, are outlined, including standards for bioinformatics pipelines, curated repositories of resistance-causing variants, phylogenetic analyses, quality control and standardized reporting.
Journal ArticleDOI
Interactions in the microbiome: communities of organisms and communities of genes
Eline Boon,Conor J. Meehan,Chr Chris Whidden,Dennis H.-J. Wong,Morgan G. I. Langille,Robert G. Beiko +5 more
TL;DR: This work identifies some promising avenues of research that are likely to yield a deeper understanding of microbial communities that shift from observation-based questions of ‘Who is there?' and 'What are they doing?' to the mechanistically driven question of 'How will they respond?'
Journal ArticleDOI
Genomic characterization of Nontuberculous Mycobacteria
Tarcisio Fedrizzi,Conor J. Meehan,Antonella Grottola,Elisabetta Giacobazzi,Giulia Fregni Serpini,Sara Tagliazucchi,A. Fabio,Clotilde Bettua,Roberto Bertorelli,Veronica De Sanctis,Fabio Rumpianesi,Monica Pecorari,Olivier Jousson,Enrico Tortoli,Nicola Segata +14 more
TL;DR: This work provides the first comprehensive characterization of the genomic diversity of NTMs and open new venues for the clinical identification of opportunistic pathogens from this genus.