C
Constantine J. Karvellas
Researcher at University of Alberta
Publications - 167
Citations - 5634
Constantine J. Karvellas is an academic researcher from University of Alberta. The author has contributed to research in topics: Liver transplantation & Medicine. The author has an hindex of 35, co-authored 136 publications receiving 4325 citations. Previous affiliations of Constantine J. Karvellas include University of Cambridge & King's College.
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Journal ArticleDOI
Association of FDA Mandate Limiting Acetaminophen (Paracetamol) in Prescription Combination Opioid Products and Subsequent Hospitalizations and Acute Liver Failure.
Babak J. Orandi,M. Chandler McLeod,Paul A. MacLennan,William M. Lee,Robert J. Fontana,Constantine J. Karvellas,Brendan M. McGuire,Cora E Lewis,Norah Terrault,Jayme E. Locke +9 more
TL;DR: In this article , the US Food and Drug Administration (FDA) announced a mandate to limit acetaminophen (paracetamol) to 325 mg/tablet in combination with opioid medications, with manufacturer compliance required by March 2014.
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Comment on Camus et al.: "Molecular adsorbent recirculating system dialysis in patients with acute liver failure who are assessed for liver transplantation".
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The Use of High Volume Plasmapheresis in Acute Liver Failure.
TL;DR: A case of a 34-year-old man presenting with ALF that led to multi-organ failure who received HVP in the intensive care unit that improved his biochemical parameters, volume status, and hemodynamics is presented.
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Coagulopathy and hemostasis management in patients undergoing liver transplantation: Defining a dynamic spectrum across phases of care
Anjana Pillai,Michael Kriss,David P. Al-Adra,Ryan M Chadha,Melissa M. Cushing,Khashayar Farsad,Brett E. Fortune,Aaron T. Hess,Robert J. Lewandowski,Mitra K. Nadim,Trevor L. Nydam,Pratima Sharma,Constantine J. Karvellas,Nicolas M. Intagliata +13 more
TL;DR: The aim is to provide a focused review of hemostatic management of the LT patient, distinguish unique aspects of the three main phases of care (before LT, perioperative, and after LT), and identify knowledge gaps and critical areas of future research.
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Serum osmolality, cerebrospinal fluid specific gravity and overt hepatic encephalopathy severity in patients with liver failure.
Eric M. Liotta,Constantine J. Karvellas,Minjee Kim,Ayush Batra,Andrew M. Naidech,Shyam Prabhakaran,Farzaneh A. Sorond,W. Taylor Kimberly,Matthew B. Maas +8 more
TL;DR: It is hypothesized that serum hyperosmolality contributes to HE during acute (ALF) and acute‐on‐chronic liver failure (ACLF) through mechanisms that affect the water and solute composition of the cerebral environment.