C
Constantine J. Karvellas
Researcher at University of Alberta
Publications - 167
Citations - 5634
Constantine J. Karvellas is an academic researcher from University of Alberta. The author has contributed to research in topics: Liver transplantation & Medicine. The author has an hindex of 35, co-authored 136 publications receiving 4325 citations. Previous affiliations of Constantine J. Karvellas include University of Cambridge & King's College.
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Journal ArticleDOI
The impact of cirrhosis in patients undergoing cardiac surgery: a retrospective observational cohort study.
Sheela Xavier,Colleen M. Norris,Amanda Ewasiuk,Demetrios J. Kutsogiannis,Sean M. Bagshaw,Sean van Diepen,Derek R. Townsend,Jayan Negendran,Constantine J. Karvellas +8 more
TL;DR: Despite having low median model for end-stage liver disease scores, this small series of cirrhotic patients undergoing cardiac surgery had significantly higher mortality rates and required more organ support postoperatively than propensity score-matched non-cirrhosis patients.
Journal ArticleDOI
Acute kidney injury: A critical care perspective for orthotopic liver transplantation.
TL;DR: Healthcare providers must develop an expertise in liver failure-related renal complications, specifically their management and perioperative implications, as well as prospective studies remain necessary to validate potential benefits.
Journal ArticleDOI
Intracranial pressure monitoring in acute liver failure: a retrospective cohort study
Constantine J. Karvellas,Oren K. Fix,Holly Battenhouse,Valerie Durkalski,Corron Sanders,William M. Lee +5 more
TL;DR: Intracranial hypertension (ICH) complicates roughly 25% of acute liver failure (ALF) patients with grade III/IV encephalopathy and monitoring is controversial due to complications in 5 to 20% and absence of documented mortality benefit.
Journal ArticleDOI
Variation in the Care of Acute Liver Failure: A Survey of Intensive Care Professionals
Filipe S. Cardoso,Mark J. W. McPhail,Constantine J. Karvellas,Valentin Fuhrmann,Nuno Germano,Georg Auzinger +5 more
TL;DR: The management of patients with ALF by ICU professionals differed substantially concerning the relevant clinical measures taken, and further education and high-quality research are warranted.