C
Corinne E. Gustafson
Researcher at Brigham and Women's Hospital
Publications - 17
Citations - 1178
Corinne E. Gustafson is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Cancer & Aquaporin 2. The author has an hindex of 10, co-authored 15 publications receiving 933 citations. Previous affiliations of Corinne E. Gustafson include Harvard University.
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Journal ArticleDOI
Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations
Raphael Bueno,Eric Stawiski,Leonard D. Goldstein,Steffen Durinck,Assunta De Rienzo,Zora Modrusan,Florian Gnad,Thong T. Nguyen,Bijay S. Jaiswal,Lucian R. Chirieac,Daniele Sciaranghella,Nhien Dao,Corinne E. Gustafson,Kiara J. Munir,Jason A. Hackney,Amitabha Chaudhuri,Ravi Gupta,Joseph Guillory,Karen Toy,Connie Ha,Ying-Jiun Chen,Jeremy Stinson,Subhra Chaudhuri,Na Zhang,Thomas D. Wu,David J. Sugarbaker,Frederic J. de Sauvage,William G. Richards,Somasekar Seshagiri +28 more
TL;DR: Recurrent gene fusions and splice alterations to be frequent mechanisms for inactivation of NF2, BAP1 and SETD2 are found and alterations in Hippo, mTOR, histone methylation, RNA helicase and p53 signaling pathways in MPMs are identified.
Journal ArticleDOI
Cellular mechanisms of aquaporin trafficking.
TL;DR: This short review summarizes recent work that addresses the regulation of AQP2 trafficking in response to vasopressin.
Journal ArticleDOI
Recycling of AQP2 occurs through a temperature- and bafilomycin-sensitive trans-Golgi-associated compartment
Corinne E. Gustafson,Toshiya Katsura,Mary McKee,Richard Bouley,James E. Casanova,Dennis Brown +5 more
TL;DR: Evidence is provided suggesting that while AQP2 shifts from an intracellular location to the cell surface in response to vasopressin, AQP 2 also constitutively recycles through a similar pathway in transfected LLC-PK(1) cells even in the absence of hormonal stimulation.
Journal ArticleDOI
Aquaporin 2 is a vasopressin-independent, constitutive apical membrane protein in rat vas deferens.
Anna Stevens,Sylvie Breton,Corinne E. Gustafson,Richard Bouley,Raoul D. Nelson,Donald E. Kohan,Dennis Brown +6 more
TL;DR: Data indicate that AQP2 is a constitutive apical membrane protein in the vas deferens, and that it is not vasopressin-regulated in this tissue.
Journal ArticleDOI
Gender-Specific Molecular and Clinical Features Underlie Malignant Pleural Mesothelioma.
Assunta De Rienzo,Michael A. Archer,Beow Y. Yeap,Nhien Dao,Daniele Sciaranghella,Antonios C. Sideris,Yifan Zheng,Alexander G. Holman,Yaoyu E. Wang,Paola Dal Cin,Jonathan A. Fletcher,Renee Rubio,Larry Croft,John Quackenbush,Peter E. Sugarbaker,Kiara J. Munir,Jesse R. Battilana,Corinne E. Gustafson,Lucian R. Chirieac,Soo Meng Ching,James R. Wong,Liang Chung Tay,Stephen Rudd,Robert Hercus,David J. Sugarbaker,William G. Richards,Raphael Bueno +26 more
TL;DR: Diverse mechanisms highly related to gender and histology appear to driveMalignant pleural mesothelioma, an aggressive cancer that occurs more frequently in men, but is associated with longer survival in women, are identified.