C
Corinne Lorenzo
Researcher at University of Toulouse
Publications - 23
Citations - 1855
Corinne Lorenzo is an academic researcher from University of Toulouse. The author has contributed to research in topics: Light sheet fluorescence microscopy & Cell cycle. The author has an hindex of 13, co-authored 22 publications receiving 1731 citations. Previous affiliations of Corinne Lorenzo include Centre national de la recherche scientifique & Paul Sabatier University.
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Journal ArticleDOI
Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy.
Cécile Delettre,Guy Lenaers,Jean-Michel Griffoin,Nadine Gigarel,Corinne Lorenzo,Pascale Belenguer,Laetitia Pelloquin,J. Grosgeorge,Claude Turc-Carel,Eric Perret,Catherine Astarie-Dequeker,Laetitia Lasquellec,B. Arnaud,Bernard Ducommun,Josseline Kaplan,Christian P. Hamel +15 more
TL;DR: A nuclear gene, OPA1, is described here a nuclear gene that maps within the candidate region and encodes a dynamin-related protein localized to mitochondria, demonstrating a role for mitochondria in retinal ganglion cell pathophysiology.
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Live cell division dynamics monitoring in 3D large spheroid tumor models using light sheet microscopy
Corinne Lorenzo,Corinne Lorenzo,Céline Frongia,Céline Frongia,Raphaël Jorand,Raphaël Jorand,Jérôme Fehrenbach,Jérôme Fehrenbach,Pierre Weiss,Pierre Weiss,Amina Maandhui,Amina Maandhui,Bernard Ducommun,Bernard Ducommun,Valérie Lobjois,Valérie Lobjois +15 more
TL;DR: A major breakthrough is reported based on the engineering of multicellular tumor spheroids expressing an histone H2B fluorescent nuclear reporter protein, and specifically designed sample holders to monitor live cell division dynamics in 3D large sp Heroids using an home-made selective-plane illumination microscope.
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Deep and clear optical imaging of thick inhomogeneous samples.
Raphaël Jorand,Gwénaële Le Corre,Gwénaële Le Corre,Jordi Andilla,Amina Maandhui,Amina Maandhui,Céline Frongia,Céline Frongia,Valérie Lobjois,Valérie Lobjois,Bernard Ducommun,Bernard Ducommun,Corinne Lorenzo,Corinne Lorenzo +13 more
TL;DR: This work combines selective plane illumination microscopy (SPIM) with wavefront sensor adaptive optics (wao) to correct distortions in three-dimensional biological imaging and to improve the quality of images from deep within thick inhomogeneous samples.
Journal ArticleDOI
Physical Association between Neuropeptide FF and μ-Opioid Receptors as a Possible Molecular Basis for Anti-opioid Activity
Michel Roumy,Corinne Lorenzo,Serge Mazères,Stéphanie Bouchet,Jean-Marie Zajac,Catherine Mollereau +5 more
TL;DR: Fluorescence resonance energy transfer and coimmunoprecipitation studies indicate that NPFF and MOP receptors are close enough to generate a basal FRET signal, suggesting an association between both receptors and the modulation of the mobility of a G-protein-coupled receptor by another one.
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High-resolution in-depth imaging of optically cleared thick samples using an adaptive SPIM
Aurore Masson,Paul Escande,Paul Escande,Céline Frongia,Céline Frongia,Grégory Clouvel,Bernard Ducommun,Bernard Ducommun,Corinne Lorenzo,Corinne Lorenzo +9 more
TL;DR: An original optical-chemical combined method based on an adaptive SPIM and a water-based clearing protocol enabling compensation for aberrations arising from RI mismatches induced by optical clearing methods and acquisition of high-resolution in-depth images of optically cleared complex thick samples such as Multi-Cellular Tumour Spheroids.