Corrie Macdonald-Wallis

TL;DR: The Avon Longitudinal Study of Children and Parents (ALSPAC) was established to understand how genetic and environmental characteristics influence health and development in parents and children.

TL;DR: Greater maternal prepregnancy weight and gestational weight gain up to 36 weeks of gestation are associated with greater offspring adiposity and adverse cardiovascular risk factors.

TL;DR: This report provides Class III evidence that the NfL electrochemiluminescence immunoassay accurately distinguishes patients with sporadic ALS from healthy controls and offers potential for N fL as a pharmacodynamic biomarker in future therapeutic trials.

TL;DR: In this article, the authors studied associations of pregnancy diabetes mellitus, hypertensive disorders of pregnancy, preterm delivery, and size for gestational age with calculated 10-year CVD risk (based on the Framingham score) and a wide range of cardiovascular risk factors measured 18 years after pregnancy (mean age at outcome assessment, 48 years).

TL;DR: GWG in all stages of pregnancy was positively associated with later BMI, WC, increased odds of overweight or obesity, and central adiposity and this support initiatives aimed at optimizing prepregnancy weight.