E
Elizabeth Gray
Researcher at University of Oxford
Publications - 53
Citations - 2978
Elizabeth Gray is an academic researcher from University of Oxford. The author has contributed to research in topics: Amyotrophic lateral sclerosis & Inflammation. The author has an hindex of 25, co-authored 46 publications receiving 2115 citations. Previous affiliations of Elizabeth Gray include Foundation for Liver Research & John Radcliffe Hospital.
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Journal ArticleDOI
Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis
Claire Bridel,van Wieringen Wn,Henrik Zetterberg,Betty M. Tijms,Charlotte E. Teunissen,José C. Álvarez-Cermeño,Ulf Andreasson,Markus Axelsson,David Bäckström,Ales Bartos,Maria Bjerke,Kaj Blennow,Kaj Blennow,A. Boxer,Lena Brundin,Joachim Burman,Tove Christensen,Lenka Fialová,Lars Forsgren,Jette L. Frederiksen,Magnus Gisslén,Elizabeth Gray,Martin Gunnarsson,Sara Hall,Oskar Hansson,Megan K. Herbert,Joel Jakobsson,Jessen-Krut J,Shorena Janelidze,Gudmundur Johannsson,Gudmundur Johannsson,Michael Jonsson,Ludwig Kappos,Mohsen Khademi,Mohsen Khademi,Michael Khalil,Jens Kuhle,Mikael Landén,Leinonen,Giancarlo Logroscino,Lu Ch,Jan Lycke,Nadia K. Magdalinou,Andrea Malaspina,Niklas Mattsson,Lieke H.H. Meeter,Mehta,Signe Modvig,Tomas Olsson,Tomas Olsson,Ross W. Paterson,Pérez-Santiago J,Fredrik Piehl,Fredrik Piehl,Pijnenburg Yal,Pyykkö Ot,Ragnarsson O,Julio C. Rojas,Romme Christensen J,Sandberg L,Carole Scherling,Jonathan M. Schott,Finn Sellebjerg,Isabella Laura Simone,Tobias Skillbäck,Stilund M,Peter Sundström,Anders Svenningsson,Rosanna Tortelli,Carla Tortorella,Alessandro Trentini,Troiano M,Martin R Turner,van Swieten Jc,Mattias Vågberg,Marcel M. Verbeek,Luisa M. Villar,Pieter Jelle Visser,Pieter Jelle Visser,Anders Wallin,Weiss A,Carsten Wikkelsö,Edward J. Wild +82 more
TL;DR: The cNfL increased with age in HC and a majority of neurological conditions, although the association was strongest in HC, and has potential to assist the differentiation of FTD from AD and PD from atypical parkinsonian syndromes.
Journal ArticleDOI
Neurofilament light chain: A prognostic biomarker in amyotrophic lateral sclerosis.
Ching-Hua Lu,Corrie Macdonald-Wallis,Elizabeth Gray,Neil Pearce,Axel Petzold,Niklas Norgren,Gavin Giovannoni,Pietro Fratta,Katie Sidle,Mark Fish,Richard W. Orrell,Robin S. Howard,Kevin Talbot,Linda Greensmith,Jens Kuhle,Martin R Turner,Andrea Malaspina +16 more
TL;DR: This report provides Class III evidence that the NfL electrochemiluminescence immunoassay accurately distinguishes patients with sporadic ALS from healthy controls and offers potential for N fL as a pharmacodynamic biomarker in future therapeutic trials.
Journal ArticleDOI
Extracellular vesicles in neurodegenerative disease - pathogenesis to biomarkers
Alexander G. Thompson,Elizabeth Gray,Sabrina M. Heman-Ackah,Imre Mäger,Kevin Talbot,Samir El Andaloussi,Samir El Andaloussi,Matthew J.A. Wood,Martin R Turner +8 more
TL;DR: The current knowledge of the biology and function of EVs is examined, the evidence for their involvement in the pathogenesis of neurodegenerative diseases is discussed, and their potential as biomarkers of disease is considered.
Journal ArticleDOI
Elevated activity and microglial expression of myeloperoxidase in demyelinated cerebral cortex in multiple sclerosis.
TL;DR: Cortical demyelination in MS is associated with increased activity of MPO, which is expressed by a CD68‐positive subset of activated microglia, suggesting that microglial production of reactive oxygen species is likely to be involved in cortical demYelination.
Journal ArticleDOI
Multicenter evaluation of neurofilaments in early symptom onset amyotrophic lateral sclerosis
Emily Feneberg,Patrick Oeckl,Petra Steinacker,Federico Verde,Christian Barro,Philip Van Damme,Elizabeth Gray,Julian Grosskreutz,Claude Jardel,Jens Kuhle,Sonja Koerner,Foudil Lamari,Maria del Mar Amador,Benjamin Mayer,Claudia Morelli,Petra Muckova,Susanne Petri,Koen Poesen,Joost Raaphorst,François Salachas,Vincenzo Silani,Beatrice Stubendorff,Martin R Turner,Marcel M. Verbeek,Jochen H. Weishaupt,Patrick Weydt,Albert C. Ludolph,Markus Otto +27 more
TL;DR: This study provides Class II evidence that CSF and serum Nf concentrations discriminate ALS with early symptom onset from other neurologic diseases.