Cristoforo Incorvaia

TL;DR: To evaluate the existing AR literature, international multidisciplinary experts with an interest in AR have produced the International Consensus statement on Allergy and Rhinology: Allergic Rhinitis (ICAR:AR).

TL;DR: The major allergen of peach is a 9-kd protein belonging to the group of lipid transfer proteins, belonging to a group of molecules involved in the defensive system of plants.

TL;DR: Clinical cross-reactivity to Prunoideae is essentially due to a common 13 kd IgE-binding component, which seems to be the most important major allergen of this subfamily, not shared with grass and birch pollen.

TL;DR: The main target of sublingual immunotherapy (SLIT) is to reduce at most the occurrence of adverse events (AE) and safety represents a critical issue when a higher dose of allergen extract than traditional subcutaneous immunotherapy is required to be effective.

TL;DR: It is demonstrated that the major allergen of kiwi fruit, Act c 1, is actinidin, a proteolytic enzyme belonging to the class of thiol-proteases.