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D Agnusdei

Researcher at Eli Lilly and Company

Publications -  25
Citations -  1970

D Agnusdei is an academic researcher from Eli Lilly and Company. The author has contributed to research in topics: Osteoporosis & Raloxifene. The author has an hindex of 18, co-authored 25 publications receiving 1816 citations.

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Quality of Life in Patients with Vertebral Fractures: Validation of the Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO)

TL;DR: The QUALEFFO questionnaire as discussed by the authors was validated in a multicenter study in seven countries and the results confirmed the decreased quality of life in patients with vertebral fractures and showed that all five domains within each questionnaire discriminated significantly between fracture cases and controls.
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The selective estrogen receptor modulator raloxifene regulates osteoclast and osteoblast activity in vitro.

TL;DR: Data show that raloxifene negatively modulates osteoclasts, and positively affects osteoblasts, suggesting not only an antiresorptive role, but also an osteoblast stimulatory role.
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Quality of life as outcome in the treatment of osteoporosis: The development of a questionnaire for quality of life by the European foundation for osteoporosis

TL;DR: Preliminary results indicate that the reproducibility is sufficient and that the questionnaire is able to discriminate between patients with vertebral osteoporosis and control subjects.