Institution
Sinai University
Education•Cairo, Egypt•
About: Sinai University is a education organization based out in Cairo, Egypt. It is known for research contribution in the topics: Cancer & Band gap. The organization has 264 authors who have published 461 publications receiving 5512 citations. The organization is also known as: SU.
Topics: Cancer, Band gap, Amorphous solid, Quantum entanglement, Architecture
Papers published on a yearly basis
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TL;DR: Recommendations are made using the GRADE (Grades of Recommendation Assessment, Development and Evaluation) system, as has been done with other Society for Vascular Surgery guideline documents.[corrected] the perioperative risk of stroke and death in asymptomatic patients must be <3% to ensure benefit for the patient.
557 citations
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Indiana University1, Indiana University – Purdue University Indianapolis2, University of Minnesota3, Emory University4, University of Kansas5, Cornell University6, Thomas Jefferson University7, Marshfield Clinic8, United States Department of Veterans Affairs9, University of California, Los Angeles10, St. Joseph's Hospital and Medical Center11, Stanford University12, New York University13, University of Pennsylvania14, University of California, San Francisco15, University of Virginia16, Sinai University17, Medtronic plc18
TL;DR: This long-term follow-up provides Class IV evidence that for patients with drug-resistant partial epilepsy, anterior thalamic stimulation is associated with a 69% reduction in seizure frequency and a 34% serious device-related adverse event rate at 5 years.
Abstract: Objective: To report long-term efficacy and safety results of the SANTE trial investigating deep brain stimulation of the anterior nucleus of the thalamus (ANT) for treatment of localization-related epilepsy. Methods: This long-term follow-up is a continuation of a previously reported trial of 5- vs 0-V ANT stimulation. Long-term follow-up began 13 months after device implantation with stimulation parameters adjusted at the investigators9 discretion. Seizure frequency was determined using daily seizure diaries. Results: The median percent seizure reduction from baseline at 1 year was 41%, and 69% at 5 years. The responder rate (≥50% reduction in seizure frequency) at 1 year was 43%, and 68% at 5 years. In the 5 years of follow-up, 16% of subjects were seizure-free for at least 6 months. There were no reported unanticipated adverse device effects or symptomatic intracranial hemorrhages. The Liverpool Seizure Severity Scale and 31-item Quality of Life in Epilepsy measure showed statistically significant improvement over baseline by 1 year and at 5 years ( p Conclusion: Long-term follow-up of ANT deep brain stimulation showed sustained efficacy and safety in a treatment-resistant population. Classification of evidence: This long-term follow-up provides Class IV evidence that for patients with drug-resistant partial epilepsy, anterior thalamic stimulation is associated with a 69% reduction in seizure frequency and a 34% serious device-related adverse event rate at 5 years.
545 citations
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McMaster University1, Eli Lilly and Company2, Columbia University3, Katholieke Universiteit Leuven4, Karolinska Institutet5, University of Oxford6, University of Sheffield7, Aarhus University Hospital8, Argerich Hospital9, Università Campus Bio-Medico10, Medical University of Graz11, University of Edinburgh12, Royal North Shore Hospital13, Sinai University14, University of Las Palmas de Gran Canaria15, Charles University in Prague16, Cambridge University Hospitals NHS Foundation Trust17, International Osteoporosis Foundation18
TL;DR: Guidance for glucocorticoid-induced osteoporosis is updated in the light of new treatments and methods of assessment, and national guidelines derived from this resource need to be tailored within the national healthcare framework of each country.
Abstract: Summary
This paper provides a framework for the development of national guidelines for the management of glucocorticoid-induced osteoporosis in men and women aged 18 years and over in whom oral glucocorticoid therapy is considered for 3 months or longer.
286 citations
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TL;DR: In this paper, different geometries of Savonius wind turbine are experimentally studied in order to determine the most effective operation parameters, it was found that, the two blades rotor is more efficient than three and four ones.
Abstract: For solving the world energy problem and the bad effect of conventional sources of energy on environment, great attention allover the world is paid towards the use of renewable energy sources. Special interest is paid towards wind energy because of its competitively.
Savonius rotor is a vertical axis wind turbine which is characterized as cheaper, simpler in construction and low speed turbine. This makes it suitable for generating mechanical energy in many countries especially in Egypt.
In this work different geometries of Savonius wind turbine are experimentally studied in order to determine the most effective operation parameters. It was found that, the two blades rotor is more efficient than three and four ones. The rotor with end plates gives higher efficiency than those of without end plates. Double stage rotors have higher performance compared to single stage rotors. The rotors without overlap ratio (β) are better in operation than those with overlap. The results show also that the power coefficient increases with rising the aspect ratio (α). The conclusions from the measurements of the static torque for each rotor at different wind speeds verify the above summarized results of this work.
231 citations
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TL;DR: This study makes the surprising finding that JA is a positive regulator of RPS2-mediated ETI, and provides evidence that NPR3 and NPR4 may mediate this effect by promoting degradation of the JA transcriptional repressor JAZs.
Abstract: It is an apparent conundrum how plants evolved effector-triggered immunity (ETI), involving programmed cell death (PCD), as a major defence mechanism against biotrophic pathogens, because ETI-associated PCD could leave them vulnerable to necrotrophic pathogens that thrive on dead host cells. Interestingly, during ETI, the normally antagonistic defence hormones, salicylic acid (SA) and jasmonic acid (JA) associated with defence against biotrophs and necrotrophs respectively, both accumulate to high levels. In this study, we made the surprising finding that JA is a positive regulator of RPS2-mediated ETI. Early induction of JA-responsive genes and de novo JA synthesis following SA accumulation is activated through the SA receptors NPR3 and NPR4, instead of the JA receptor COI1. We provide evidence that NPR3 and NPR4 may mediate this effect by promoting degradation of the JA transcriptional repressor JAZs. This unique interplay between SA and JA offers a possible explanation of how plants can mount defence against a biotrophic pathogen without becoming vulnerable to necrotrophic pathogens.
222 citations
Authors
Showing all 268 results
Name | H-index | Papers | Citations |
---|---|---|---|
Bart Barlogie | 126 | 779 | 57803 |
Gary E. Striker | 67 | 220 | 18293 |
John D. Puskas | 64 | 303 | 17131 |
Michael K. Parides | 54 | 155 | 12491 |
Peter L. Faries | 49 | 270 | 9278 |
Brendan G. Carr | 42 | 184 | 8115 |
Baron S. Lonner | 40 | 206 | 4449 |
A.M. Abdelghany | 38 | 196 | 3548 |
Mary M. McKay | 38 | 102 | 4617 |
Mohsen Jalali | 37 | 192 | 4825 |
Kalmon D. Post | 35 | 83 | 4092 |
Said S.E.H. Elnashaie | 34 | 167 | 3823 |
Gareth R. John | 32 | 50 | 4727 |
Mohammad Amin | 23 | 57 | 1402 |
Pradip R. Shetye | 21 | 73 | 1254 |