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Dan L. Longo

Researcher at Harvard University

Publications -  730
Citations -  59268

Dan L. Longo is an academic researcher from Harvard University. The author has contributed to research in topics: Antigen & Immune system. The author has an hindex of 125, co-authored 697 publications receiving 56085 citations. Previous affiliations of Dan L. Longo include University of Nebraska Omaha & Yale Cancer Center.

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Peripheral destruction of platelets in chronic lymphocytic leukemia: Recognition, prognosis and therapeutic implicatio

TL;DR: In patients with chronic lymphocytic leukemia and depressed platelet counts, it is important to discriminate between the thrombocytopenia due to bone marrow replacement with abnormal lymphocytes and that caused by increased peripheral destruction of platelets.
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Treatment of Hodgkin's disease.

TL;DR: The available data support the hypothesis proposed by Smithers that Hodgkin's disease appears to be a systemic disorder of the lymphatic system as mentioned in this paper, and it is best that either chemotherapy or radiotherapy be used alone except in patients who have massive mediastinal disease and for whom combinations of radiotherapy and combination chemotherapy are superior.
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Preserved learning and memory following 5-fluorouracil and cyclophosphamide treatment in rats

TL;DR: The results contribute to a growing literature suggesting that learning and memory mediated by the hippocampus can be relatively resistant to chemotherapy, and may need to focus on assessments of processing speed, executive function and attention.
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Detection of c-mos proto-oncogene expression in human cells.

TL;DR: The detection of c-mos protein in a human neuroblastoma cell line, SK-N-BE2 (BE2) is reported and it is shown that c-Mos proteins are expressed in cervical carcinoma-derived cell lines and suggests a fundamental role for the c-mo proto-oncogene.
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Selection of antigen-specific, idiotype-positive B cells in transgenic mice expressing a rearranged M167-mu heavy chain gene.

TL;DR: Flow cytometric analysis of antigen-specific, idiotype-positive (id+), B cell development in transgenic mice expressing a rearranged M167-mu gene shows that large numbers of phosphocholine (PC)-specific, M 167-id+ B cells develop in the spleen and bone marrow of these mice.