D
Dan L. Longo
Researcher at Harvard University
Publications - 730
Citations - 59268
Dan L. Longo is an academic researcher from Harvard University. The author has contributed to research in topics: Antigen & Immune system. The author has an hindex of 125, co-authored 697 publications receiving 56085 citations. Previous affiliations of Dan L. Longo include University of Nebraska Omaha & Yale Cancer Center.
Papers
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Journal ArticleDOI
Interleukin-2 and human monocyte activation.
TL;DR: The effects of IL‐2 on human monocytes, the differential expression and modulation of theIL‐2R subunits, and their relationship with the responsiveness of monocyte activation by inhibitory signals are discussed.
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Transient Improvement in Cognitive Function and Synaptic Plasticity in Rats Following Cancer Chemotherapy
Garrick D. Lee,Dan L. Longo,Yue Wang,Joseph M. Rifkind,Lilanie Abdul-Raman,Jacek Mamczarz,Kara B. Duffy,Edward L. Spangler,Dennis D. Taub,Mark P. Mattson,Donald K. Ingram +10 more
TL;DR: Despite toxicity accompanying chemotherapy, no evidence of impaired cognitive performance emerged after recovery from chemotherapy, and cyclophosphamide- and 5FU-treated rats showed significantly better maze performance compared with controls.
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Immunomodulators in Clinical Medicine
TL;DR: A major difficulty limiting the use of immunomodulators in clinical medicine has been the complexity of the immunoregulatory network in which modulation of one component usually perturbs another component, and this work aims to address this problem.
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Changes in expression of signal transduction proteins in T lymphocytes of patients with leprosy.
Arnold H. Zea,Arnold H. Zea,Maria Teresa Ochoa,Paritosh Ghosh,Dan L. Longo,W. Gregory Alvord,Liliana Valderrama,Rafael Falabella,Linda K. Harvey,Nancy G. Saravia,Luis Hernando Moreno,Augusto C. Ochoa,Augusto C. Ochoa +12 more
TL;DR: Major alterations in the expression of signal transduction molecules in T cells of leprosy patients were demonstrated and might improve the understanding of the T-cell dysfunction observed inLeprosy and other infectious diseases and consequently might lead to better immunologic evaluation of patients.
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Histogenetic correlations between subcategories of small noncleaved cell lymphomas.
TL;DR: The results indicate that the subtle histologic differences that distinguish subcategories of SNCL are significant biologically and reflect distinct molecular mechanisms of lymphomagenesis and confirm the remarkable molecular genetic homogeneity of the sBT group.