Daniel L. Mace

TL;DR: Methods that combine microarray expression profiles of a high-resolution set of developmental time points within a single Arabidopsis root and a comprehensive map of nearly all root cell types demonstrate transcriptionally rich and complex programs that define Arabidrosis root development in both space and time.

TL;DR: The transcriptional response to high salinity of different cell layers and developmental stages of the Arabidopsis root is characterized and it is found that transcriptional responses are highly constrained by developmental parameters.

TL;DR: The results suggest that, for Arabidopsis TFs, upstream noncoding sequences are major contributors to mRNA expression pattern establishment, but modulation of transcription factor protein expression pattern after transcription is relatively frequent.

TL;DR: This work determined the genomic distribution of binding sites for 92 transcription factors and regulatory proteins across multiple stages of Caenorhabditis elegans development by performing 241 ChIP-seq (chromatin immunoprecipitation followed by sequencing) experiments and produced a spatiotemporally resolved metazoan transcription factor binding map.

TL;DR: A microfluidics device, the RootArray, in which 64 Arabidopsis thaliana seedlings can be grown and their roots imaged by confocal microscopy over several days without manual intervention, and decoupled acquisition from analysis to achieve high throughput.