D
Daniel P. Ferris
Researcher at University of California, Los Angeles
Publications - 9
Citations - 1779
Daniel P. Ferris is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Mesoporous silica & Drug delivery. The author has an hindex of 8, co-authored 9 publications receiving 1648 citations.
Papers
More filters
Journal ArticleDOI
Noninvasive remote-controlled release of drug molecules in vitro using magnetic actuation of mechanized nanoparticles
Courtney R. Thomas,Daniel P. Ferris,Jae Hyun Lee,Eun Joo Choi,Mi Hyeon Cho,Eun Sook Kim,J. Fraser Stoddart,Jeon Soo Shin,Jinwoo Cheon,Jeffrey I. Zink +9 more
TL;DR: A novel material that incorporates zinc-doped iron oxide nanocrystals within a mesoporous silica framework that has been surface-modified with pseudorotaxanes is described, which promises to be a noninvasive, externally controlled drug delivery system with cancer-killing properties.
Journal ArticleDOI
Light-Operated Mechanized Nanoparticles
Daniel P. Ferris,Yanli Zhao,Niveen M. Khashab,Hussam A. Khatib,J. Fraser Stoddart,Jeffrey I. Zink +5 more
TL;DR: Mesoporous silica nanoparticles modified by azobenzene derivatives, capable of storing small molecules and releasing them following light irradiation, have been fabricated and characterized.
Journal ArticleDOI
Synthesis of Biomolecule-Modified Mesoporous Silica Nanoparticles for Targeted Hydrophobic Drug Delivery to Cancer Cells
Daniel P. Ferris,Jie Lu,Chris M. Gothard,Rolando E. Yanes,Courtney R. Thomas,John Carl Olsen,J. Fraser Stoddart,Fuyuhiko Tamanoi,Jeffrey I. Zink +8 more
TL;DR: These results demonstrate successful biomolecular-targeted hydrophobic drug delivery carriers that selectively target specific cancer cells and result in enhanced drug delivery and cell mortality.
Journal ArticleDOI
Targeted Intracellular Delivery of Antituberculosis Drugs to Mycobacterium tuberculosis-Infected Macrophages via Functionalized Mesoporous Silica Nanoparticles
Daniel L. Clemens,Bai-Yu Lee,Min Xue,Courtney R. Thomas,Huan Meng,Daniel P. Ferris,Andre E. Nel,Jeffrey I. Zink,Marcus A. Horwitz +8 more
TL;DR: It is demonstrated that the isoniazid delivered by MSNP equipped with pH-operated nanovalves kill M. tuberculosis within macrophages significantly more effectively than an equivalent amount of free drug.
Journal ArticleDOI
Involvement of lysosomal exocytosis in the excretion of mesoporous silica nanoparticles and enhancement of the drug delivery effect by exocytosis inhibition.
Rolando E. Yanes,Derrick Tarn,Angela A. Hwang,Daniel P. Ferris,Sean P. Sherman,Courtney R. Thomas,Jie Lu,April D. Pyle,Jeffrey I. Zink,Fuyuhiko Tamanoi +9 more
TL;DR: The exocytosis of phosphonate modified mesoporous silica nanoparticles (P-MSNs) is demonstrated and lysosomal exocyTosis is identified as the mechanism responsible for this event.