Daniel Zicha

TL;DR: It is reported that mural cells require ephrin-B2, a ligand for Eph receptor tyrosine kinases, for normal association with small-diameter blood vessels (microvessels), and the results indicate that the role of e phrin- B2 and EphB receptors in these processes involves Crk-p130(CAS) signaling and suggest that ephin-B1 has some cell-cell-contact-independent functions.

TL;DR: It is provided the first evidence that PKCα or a PKC α‐associated serine/threonine kinase can phosphorylate the ERM C‐terminal threonine residue within a kinase–ezrin molecular complex in vivo.

TL;DR: The protein network generation and subsequent network analysis used here, were shown to be useful for highlighting key proteins involved in metastasis, and can be extended to other species, thereby suggesting possible pathways around proteins of interest.

TL;DR: It is shown that DNA polymerase ι (polι), like polη, associates with the replication machinery and accumulates at stalled replication forks following DNA‐damaging treatment, and that the C‐terminal 224 amino acids of polι are sufficient for both the interaction withpolη and accumulation in replication foci.

TL;DR: It is concluded that talin is essential for β1 integrin expression and focal adhesion assembly in undifferentiated ES cells, but that a subset of differentiated cells are talin independent for both characteristics.