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Daniele Bellavia
Researcher at University of Palermo
Publications - 54
Citations - 1210
Daniele Bellavia is an academic researcher from University of Palermo. The author has contributed to research in topics: Medicine & Osteoporosis. The author has an hindex of 16, co-authored 41 publications receiving 813 citations.
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Interleukin 3- receptor targeted exosomes inhibit in vitro and in vivo Chronic Myelogenous Leukemia cell growth.
Daniele Bellavia,Stefania Raimondo,Giovanna Calabrese,Stefano Forte,Marta Cristaldi,Agostina Patinella,Lorenzo Memeo,Mauro Manno,Samuele Raccosta,Patrizia Diana,Girolamo Cirrincione,Gianluca Giavaresi,Francesca Monteleone,Simona Fontana,Giacomo De Leo,Riccardo Alessandro +15 more
TL;DR: It is shown that IL3L exosomes, loaded with Imatinib or with BCR-ABL siRNA, are able to target CML cells and inhibit in vitro and in vivo cancer cell growth.
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Involvement of multiple myeloma cell-derived exosomes in osteoclast differentiation.
Lavinia Raimondi,Angela De Luca,Nicola Amodio,Mauro Manno,Samuele Raccosta,Simona Taverna,Daniele Bellavia,Flores Naselli,Simona Fontana,Odessa Schillaci,Roberto Giardino,Milena Fini,Pierfrancesco Tassone,Alessandra Santoro,Giacomo De Leo,Gianluca Giavaresi,Riccardo Alessandro,Riccardo Alessandro +17 more
TL;DR: The data indicate that MM-exosomes modulate OCs function and differentiation, and positively modulate pre-osteoclast migration, through the increasing of CXCR4 expression and trigger a survival pathway.
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Deregulated miRNAs in bone health: Epigenetic roles in osteoporosis.
Daniele Bellavia,A. De Luca,Valeria Carina,Viviana Costa,Lavinia Raimondi,Francesca Salamanna,Riccardo Alessandro,Milena Fini,Gianluca Giavaresi +8 more
TL;DR: An exhaustive overview of miRNAs with experimentally validated targets involved in bone homeostasis and highlight their possible role in osteoporosis development is given.
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Osteosarcoma cell-derived exosomes affect tumor microenvironment by specific packaging of microRNAs
Lavinia Raimondi,Angela De Luca,Alessia Gallo,Viviana Costa,Giovanna Russelli,Nicola Cuscino,Mauro Manno,Samuele Raccosta,Valeria Carina,Daniele Bellavia,Alice Conigliaro,Riccardo Alessandro,Milena Fini,Pier Giulio Conaldi,Gianluca Giavaresi +14 more
TL;DR: In this paper, the authors investigated the contribution of exosomes inside the micro-environment, and found that exosome promoted osteoclasts differentiation and bone resorption activity and increased angiogenic markers expression.
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Anti-proliferative and pro-apoptotic activity of whole extract and isolated indicaxanthin from Opuntia ficus-indica associated with re-activation of the onco-suppressor p16INK4a gene in human colorectal carcinoma (Caco-2) cells
Flores Naselli,Luisa Tesoriere,Fabio Caradonna,Daniele Bellavia,Alessandro Attanzio,Carla Gentile,M. A. Livrea +6 more
TL;DR: Dietary cactus pear fruit and Ind may have chemo-preventive potential in intestinal cells and decrease of hyper-phosphorylated retinoblastoma was observed, with unaltered level of the cycline-dependent kinase CDK4.