S
Simona Taverna
Researcher at National Research Council
Publications - 54
Citations - 2616
Simona Taverna is an academic researcher from National Research Council. The author has contributed to research in topics: Microvesicles & Medicine. The author has an hindex of 21, co-authored 41 publications receiving 2133 citations. Previous affiliations of Simona Taverna include Queen Mary University of London & University of Palermo.
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Journal ArticleDOI
Exosomes from metastatic cancer cells transfer amoeboid phenotype to non-metastatic cells and increase endothelial permeability: their emerging role in tumor heterogeneity
Odessa Schillaci,Simona Fontana,Francesca Monteleone,Simona Taverna,Maria Antonietta Di Bella,Dolores Di Vizio,Riccardo Alessandro,Riccardo Alessandro +7 more
TL;DR: The results demonstrate that in a heterogeneous context exosomes released by aggressive sub-clones can contribute to accelerate tumor progression by spreading malignant properties that affect both the tumor cell plasticity and the endothelial cell behavior.
Journal ArticleDOI
Exosomes released by K562 chronic myeloid leukemia cells promote angiogenesis in a src-dependent fashion
Marco Mineo,Marco Mineo,Susan H. Garfield,Simona Taverna,A. Flugy,Giacomo De Leo,Riccardo Alessandro,Elise C. Kohn +7 more
TL;DR: The inhibitory effect of dasatinib on exosome production and vascular differentiation and signaling reveals a key role for Src in both the leukemia and its microenvironment.
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Role of exosomes released by chronic myelogenous leukemia cells in angiogenesis
Simona Taverna,A. Flugy,Laura Saieva,Elise C. Kohn,Alessandra Santoro,Serena Meraviglia,Giacomo De Leo,Riccardo Alessandro +7 more
TL;DR: The results suggest for the first time that exosomes released from CML cells directly affect endothelial cells modulating the process of neovascularization.
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Liquid biopsies in lung cancer: The new ambrosia of researchers
Christian Rolfo,Marta Castiglia,David S. Hong,Riccardo Alessandro,Inge Mertens,Geert Baggerman,Karen Zwaenepoel,Ignacio Gil-Bazo,Francesco Passiglia,Anna Paola Carreca,Simona Taverna,Renza Vento,Marc Peeters,Antonio Russo,Patrick Pauwels +14 more
TL;DR: This review will focus its attention on circulating tumor cells, circulating tumor DNA, exosomes and secretomes with the aim to underlie their usefulness and potential application in a clinical setting for lung cancer patient management.
Journal ArticleDOI
Involvement of multiple myeloma cell-derived exosomes in osteoclast differentiation.
Lavinia Raimondi,Angela De Luca,Nicola Amodio,Mauro Manno,Samuele Raccosta,Simona Taverna,Daniele Bellavia,Flores Naselli,Simona Fontana,Odessa Schillaci,Roberto Giardino,Milena Fini,Pierfrancesco Tassone,Alessandra Santoro,Giacomo De Leo,Gianluca Giavaresi,Riccardo Alessandro,Riccardo Alessandro +17 more
TL;DR: The data indicate that MM-exosomes modulate OCs function and differentiation, and positively modulate pre-osteoclast migration, through the increasing of CXCR4 expression and trigger a survival pathway.