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Danielle Bousquet-Moore
Researcher at University of Connecticut Health Center
Publications - 7
Citations - 668
Danielle Bousquet-Moore is an academic researcher from University of Connecticut Health Center. The author has contributed to research in topics: Long-term potentiation & Neuropeptide. The author has an hindex of 6, co-authored 7 publications receiving 583 citations. Previous affiliations of Danielle Bousquet-Moore include Duke University.
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Journal ArticleDOI
Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3
Xiaoming Wang,Portia A. McCoy,Ramona M. Rodriguiz,Yanzhen Pan,H. Shawn Je,Adam C. Roberts,Caroline J. Kim,Janet Berrios,Jennifer S. Colvin,Danielle Bousquet-Moore,Isabel Lorenzo,Gang Yi Wu,Richard J. Weinberg,Michael D. Ehlers,Michael D. Ehlers,Benjamin D. Philpot,Arthur L. Beaudet,William C. Wetsel,Yong-hui Jiang +18 more
TL;DR: It is concluded that loss of major Shank3 species produces biochemical, cellular and morphological changes, leading to behavioral abnormalities in mice that bear similarities to human ASD patients with SHANK3 mutations.
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Peptidylgycine α-amidating monooxygenase and copper: a gene-nutrient interaction critical to nervous system function.
TL;DR: Data is reviewed indicating that genetic reduction of PAM expression and mild copper deficiency in mice cause similar alterations in several physiological functions known to be regulated by neuropeptides: thermal regulation, seizure sensitivity, and anxiety‐like behavior.
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Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction.
Danielle Bousquet-Moore,Joseph R. Prohaska,Eduardo A. Nillni,Traci A. Czyzyk,William C. Wetsel,Richard E. Mains,Betty A. Eipper +6 more
TL;DR: Altered copper homeostasis in PAM(+/-) mice suggested a role for PAM in the cell type specific regulation of copper metabolism, and Physiological functions sensitive to genetic limitations of PAM that are reversed by supplemental copper and mimicked by copper deficiency may serve as indicators of marginal copper deficiency.
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Reversal of Physiological Deficits Caused by Diminished Levels of Peptidylglycine α-Amidating Monooxygenase by Dietary Copper
Danielle Bousquet-Moore,Xin-Ming Ma,Eduardo A. Nillni,Traci A. Czyzyk,John E. Pintar,Betty A. Eipper,Richard E. Mains +6 more
TL;DR: The results suggest that dietary deficiency of copper, coupled with genetic deficits in PAM, could result in physiological deficits in humans.
Journal ArticleDOI
Haploinsufficiency in Peptidylglycine α-Amidating Monooxygenase Leads to Altered Synaptic Transmission in the Amygdala and Impaired Emotional Responses
Eric D. Gaier,Ramona M. Rodriguiz,Xin-Ming Ma,Shobhana Sivaramakrishnan,Danielle Bousquet-Moore,William C. Wetsel,Betty A. Eipper,Richard E. Mains +7 more
TL;DR: Emotionality is evaluated and molecular and cellular responses that characterize neurophysiological differences in the PAM+/− amygdala are examined to elucidate neurophysiology correlates of the fear behavioral phenotypes.