D
David C. Dale
Researcher at University of Washington
Publications - 419
Citations - 26111
David C. Dale is an academic researcher from University of Washington. The author has contributed to research in topics: Neutropenia & Congenital Neutropenia. The author has an hindex of 85, co-authored 406 publications receiving 24613 citations. Previous affiliations of David C. Dale include National Institutes of Health & Fred Hutchinson Cancer Research Center.
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Journal ArticleDOI
The hypereosinophilic syndrome: analysis of fourteen cases with review of the literature.
TL;DR: A group of 14 patients had hematologic, cardiac, and neurologic abnormalities attributable to this disease, and patient survival and response to chemotherapy was significantly better in this group than in previously reported patients.
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Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist
Hal E. Broxmeyer,Christie M. Orschell,D. Wade Clapp,Giao Hangoc,Scott Cooper,P. Artur Plett,W. Conrad Liles,Xiaxin Li,Barbara Graham-Evans,Timothy B. Campbell,Gary Calandra,Gary Bridger,David C. Dale,Edward F. Srour +13 more
TL;DR: Results support the hypothesis that the CXCL12-CXCR4 axis is involved in marrow retention of HSCs and HPCs, and demonstrate the clinical potential of AMD3100 for HSC mobilization.
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Glucocorticosteroid Therapy: Mechanisms of Action and Clinical Considerations
TL;DR: The administration of glucocorticosteroids results in a wide range of effects on inflammatory and immunologically mediated disease processes, and the corticosteroid regimen should be adjusted to attain maximal therapeutic benefit with minimal adverse side effects.
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Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist.
W. Conrad Liles,W. Conrad Liles,Hal E. Broxmeyer,Hal E. Broxmeyer,Elin Rodger,Elin Rodger,Brent L. Wood,Brent L. Wood,Kai Hübel,Kai Hübel,Scott Cooper,Scott Cooper,Giao Hangoc,Giao Hangoc,Gary Bridger,Gary Bridger,Geoffrey W. Henson,Geoffrey W. Henson,Gary Calandra,Gary Calandra,David C. Dale +20 more
TL;DR: Findings suggest potential clinical application of AMD3100 for CD34+ cell mobilization and collection for hematopoietic stem cell transplantation.
Journal ArticleDOI
The phagocytes: neutrophils and monocytes
TL;DR: Over the last 50 years, many genetic and molecular disorders of phagocytes have been identified, leading to improved diagnosis and treatment of conditions which predispose patients to the risk of recurrent fevers and infectious diseases.