D
David J. Margolis
Researcher at University of Pennsylvania
Publications - 581
Citations - 74527
David J. Margolis is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Population & Atopic dermatitis. The author has an hindex of 97, co-authored 521 publications receiving 62556 citations. Previous affiliations of David J. Margolis include Rutgers University & Harvard University.
Papers
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Journal ArticleDOI
Association of KIR Genes and MHC Class I Ligands with Atopic Dermatitis.
David J. Margolis,Nandita Mitra,Ole Hoffstad,Brian S. Kim,Dimitri S. Monos,Dimitri S. Monos,Elizabeth J. Phillips +6 more
TL;DR: In this article, the authors identify potential associations between NK cell function and AD by evaluating variation in the presence of KIR genes as well as KIR gene interactions with the appropriate HLA class I KIR-specific ligands.
Journal ArticleDOI
Reliability and validity of genotyping filaggrin null mutations.
David J. Margolis,Andrea J. Apter,Nandita Mitra,Jayanta Gupta,Ole Hoffstad,Maryte Papadopoulos,Timothy R. Rebbeck,Stephanie F. MacCallum,Linda E. Campbell,Aileen Sandilands,W.H. Irwin McLean +10 more
TL;DR: The goal of this study was to compare the reliability (the consistency of and ability to replicate a measurement) and validity (the ability of a measurement to identify the correct event) of these two techniques.
Journal ArticleDOI
Filaggrin sequencing and bioinformatics tools.
TL;DR: It is shown that genotyping using a popular older informatics program is problematic and publications that used the older program likely do not properly capture all FLG variants.
Journal ArticleDOI
Lower-extremity amputation risk is associated with variation in behavioral risk factor surveillance system responses.
TL;DR: A cross-sectional prevalence study of merged data from the U.S. Census, Medicare parts A and B, and the Behavioral Risk Factor Surveillance System found that regional variation in the rate of lower-extremity amputation (LEA) is associated with health behaviors.
Journal ArticleDOI
Human leukocyte antigen class-I variation is associated with atopic dermatitis: A case-control study
David J. Margolis,Nandita Mitra,Jamie L. Duke,Ronald Berna,J.D. Margolis,Ole Hoffstad,Brian S. Kim,A.C. Yan,Andrea L. Zaenglein,Z.C. Chiesa Fuxench,Amalia Dinou,Jenna R. Wasserman,Nikolaos Tairis,Timothy Mosbruger,Deborah Ferriola,Georgios Damianos,Ioanna Kotsopoulou,Dimitrios Monos,Dimitrios Monos +18 more
TL;DR: In this article, a case-control study was designed to evaluate HLA class I allelic variation and binding pocket polymorphisms, using next generation sequencing on 464 subjects with AD and 388 without AD.