David J. P. Ferguson

TL;DR: By combining NTA with fluorescence measurement it is demonstrated that vesicles can be labeled with specific antibody-conjugated quantum dots, allowing their phenotype to be determined, demonstrating that NTA is far more sensitive than conventional flow cytometry.

TL;DR: It is shown that NOD2-mediated autophagy is required for both bacterial handling and generation of major histocompatibility complex (MHC) class II antigen-specific CD4+ T cell responses in DCs, and defects in this pathway in Crohn's disease DCs are revealed.

TL;DR: The shikimate pathway is an attractive target for herbicides and antimicrobial agents because it is essential in algae, higher plants, bacteria and fungi, but absent from mammals as discussed by the authors.

TL;DR: It is shown that mouse LYVE-1 both binds and internalizes hyaluronan in transfected 293T fibroblasts in vitro and demonstrated using immunoelectron microscopy that it is distributed equally among the luminal and abluminal surfaces of lymphatic vessels in vivo.

TL;DR: This study developed a method for highly efficient purification of rhoptries from one of the best studied Apicomplexa, Toxoplasma gondii, and carried out a detailed proteomic analysis using mass spectrometry that identified 38 novel proteins that are likely to play a key role in the ability of the parasite to invade and co-opt the host cell for its own survival and growth.