D
David Neary
Researcher at Salford Royal NHS Foundation Trust
Publications - 220
Citations - 33304
David Neary is an academic researcher from Salford Royal NHS Foundation Trust. The author has contributed to research in topics: Frontotemporal dementia & Dementia. The author has an hindex of 78, co-authored 206 publications receiving 31481 citations. Previous affiliations of David Neary include University of Salford & Manchester Academic Health Science Centre.
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Journal ArticleDOI
18F-Florbetapir PET in Patients with Frontotemporal Dementia and Alzheimer Disease
Christopher Kobylecki,Tobias Langheinrich,Rainer Hinz,Emma R.L.C. Vardy,Gavin Brown,Maria-Elena Martino,Cathleen Haense,Anna Richardson,Alexander Gerhard,Jose Anton-Rodriguez,Julie S. Snowden,David Neary,Michael J. Pontecorvo,Karl Herholz +13 more
TL;DR: Cortical 18F-florbetapir uptake is low in most FTD patients, providing good discrimination from AD, however, visual rating of FTD scans was challenging, with a higher rate of discordance between interpreters than in AD and control subjects.
Journal ArticleDOI
The effect of tau genotype on clinical features in FTDP-17.
Yasuhiko Baba,Yoshio Tsuboi,Matt Baker,Ryan J. Uitti,Mike Hutton,Dennis W. Dickson,Matthew J. Farrer,John D. Putzke,Bryan K. Woodruff,Bernardino Ghetti,Jill R. Murrell,Bradley F. Boeve,Ronald C. Petersen,Patrice Verpillat,Alexis Brice,Marie Bernadette Delisle,O. Rascol,Kunimasa Arima,Maurice W. Dysken,Minoru Yasuda,T. Kobayashi,Nobuhiko Sunohara,Osamu Komure,Sadako Kuno,Anne D. Sperfeld,Gabriela Stoppe,Jürgen Kohlhase,Stuart Pickering-Brown,David Neary,Orso Bugiani,Zbigniew K. Wszolek +30 more
TL;DR: The results suggest that tau genotype does not influence the disease course, however, it may predispose to a specific clinical sign in the early stage of FTDP-17.
Journal ArticleDOI
Nuclear carrier and RNA-binding proteins in frontotemporal lobar degeneration associated with fused in sarcoma (FUS) pathological changes.
Yvonne S Davidson,Andrew C Robinson,Quan Hu,Manjari Mishra,Atik Baborie,Evelyn Jaros,Robert H. Perry,Nigel J. Cairns,Anna Richardson,Alexander Gerhard,David Neary,Julie S. Snowden,Eileen H. Bigio,David M. A. Mann +13 more
TL;DR: Y. Robinson, Q. Hu, M. H. Perry, N. Neary, J. S. Richardson, A. Gerhard, D. J. Jaros, R. H., and D. A. Mann (2013) Neuropathology and Applied Neurobiology39, 157–165.
Journal ArticleDOI
Co-Occurrence of Language and Behavioural Change in Frontotemporal Lobar Degeneration.
Jennifer M. Harris,Matthew Jones,Claire Gall,Anna Richardson,David Neary,Daniel du Plessis,Piyali Pal,David M. A. Mann,Julie S. Snowden,Jennifer C. Thompson +9 more
TL;DR: Behavioural and language symptoms frequently co-occur in patients with frontotemporal lobar degeneration (FTLD) spectrum pathology and current classifications, which separate behavioural and language syndromes, do not reflect thisCo-occurrence.
Journal ArticleDOI
Exome sequencing identifies 2 novel presenilin 1 mutations (p.L166V and p.S230R) in British early-onset Alzheimer's disease
Celeste Sassi,Celeste Sassi,Rita Guerreiro,Rita Guerreiro,Raphael Gibbs,Raphael Gibbs,Jinhui Ding,Michelle K. Lupton,Claire Troakes,Katie Lunnon,Safa Al-Sarraj,Kristelle Brown,Chirstopher Medway,Jenny Lord,James Turton,David M. A. Mann,Julie S. Snowden,David Neary,Jeniffer Harris,Jose Bras,Kevin Morgan,John Powell,Andrew B. Singleton,John Hardy +23 more
TL;DR: A comprehensive catalog of rare pathogenic variants in the AD Mendelian genes is pivotal for a premortem diagnosis of autosomal dominant EOAD and for the differential diagnosis with other early onset dementias such as frontotemporal dementia (FTD) and Creutzfeldt-Jakob disease (CJD).