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David S. Medich
Researcher at University of Pittsburgh
Publications - 28
Citations - 1766
David S. Medich is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Colorectal cancer & Hazard ratio. The author has an hindex of 14, co-authored 26 publications receiving 1571 citations. Previous affiliations of David S. Medich include Allegheny General Hospital.
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Journal ArticleDOI
Organ preservation for clinical T2N0 distal rectal cancer using neoadjuvant chemoradiotherapy and local excision (ACOSOG Z6041): results of an open-label, single-arm, multi-institutional, phase 2 trial
Julio Garcia-Aguilar,Lindsay A. Renfro,Oliver S. Chow,Qian Shi,Xiomara W. Carrero,Patricio B. Lynn,Charles R. Thomas,Emily Chan,Peter A. Cataldo,Jorge E. Marcet,David S. Medich,Craig S. Johnson,Samuel Oommen,Bruce G. Wolff,Alessio Pigazzi,Shane M McNevin,Roger K Pons,Ronald Bleday +17 more
TL;DR: The data suggest that nCRT followed by LE may be considered as an organ-preserving alternative in carefully selected patients with clinically-staged T2N0 tumours who refuse, or are not candidates for, transabdominal resection.
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A Phase II Trial of Neoadjuvant Chemoradiation and Local Excision for T2N0 Rectal Cancer: Preliminary Results of the ACOSOG Z6041 Trial
Julio Garcia-Aguilar,Qian Shi,Charles R. Thomas,Emily Chan,Peter A. Cataldo,Jorge E. Marcet,David S. Medich,Alessio Pigazzi,Samuel Oommen,Mitchell C. Posner +9 more
TL;DR: CRT before LE for T2N0 tumors results in a high pathologic complete response rate and negative resection margins, however, complications during CRT and after LE are high.
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A randomized multicenter trial to compare long-term functional outcome, quality of life, and complications of surgical procedures for low rectal cancers.
Victor W. Fazio,Massarat Zutshi,Feza H. Remzi,Yann Parc,Reinhard Ruppert,Alois Fürst,James P. Celebrezze,Susan Galanduik,Guy R. Orangio,Neil Hyman,Leslie Bokey,Emmanuel Tiret,Boris Kirchdorfer,David S. Medich,Marcus Tietze,Tracy L. Hull,Jeff Hammel +16 more
TL;DR: In patients undergoing a restorative resection for low rectal cancer, a colonic JP offers significant advantages in function over an SA or a coloplasty, and in patients who cannot have a pouch,coloplasty seems not to improve the bowel function of patients over that with an SA.
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Hand-assisted Laparoscopic Surgery (hals) With the Handport System: Initial Experience With 68 Patients
Demetrius E. M. Litwin,Ara Darzi,Jacek Jakimowicz,John J. Kelly,Dag Arvidsson,Paul D. Hansen,Mark P. Callery,Ronald Denis,Dennis L. Fowler,David S. Medich,Michael O'Reilly,Henry Atlas,Jacques M. Himpens,Lee L. Swanstrom,Elias J. Arous,Piet Pattyn,Steven M. Yood,Rocco Ricciardi,Andras Sandor,William C. Meyers +19 more
TL;DR: The hand-assisted technique appeared to be useful in minimally invasive colorectal surgery, splenectomy for splenomegaly, living-related donor nephrectomy, and procedures considered too complex for a laparoscopic approach.
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Endoglin (CD105) and vascular endothelial growth factor as prognostic markers in colorectal cancer
TL;DR: Endoglin staining, by staining higher numbers of the proliferating vessels in colon carcinoma, is a more specific and sensitive marker for tumor angiogenesis than the commonly used panendothelial markers.