D
David W. Holt
Researcher at Analytical Services
Publications - 1
Citations - 111
David W. Holt is an academic researcher from Analytical Services. The author has contributed to research in topics: Therapeutic drug monitoring & Transplantation. The author has an hindex of 1, co-authored 1 publications receiving 82 citations.
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Therapeutic Drug Monitoring of Everolimus: A Consensus Report
Maria Shipkova,Dennis A. Hesselink,David W. Holt,Eliane M. Billaud,Teun van Gelder,Paweł K. Kunicki,Mercè Brunet,Klemens Budde,Markus J. Barten,Paolo De Simone,Eberhard Wieland,Olga López,Satohiro Masuda,Christoph Seger,Nicolas Picard,Michael Oellerich,Loralie J. Langman,Pierre Wallemacq,Raymond G. Morris,Carol Thompson,P. Marquet +20 more
TL;DR: EVR trough concentrations (C0) demonstrate a good relationship with overall exposure, providing a simple and reliable index for TDM, and a fully validated liquid chromatography tandem mass spectrometry assay is the preferred method for determination of EVR C0.