Christoph Seger

TL;DR: It is concluded that considerable advances in the different fields of tacrolimus monitoring have been achieved during this last decade, and the Expert Committee concludes that Continued efforts should focus on the opportunities to implement in clinical routine the combination of new standardized PK approaches with PG, and valid biomarkers to further personalize tacolimus therapy and to improve long-term outcomes for treated patients.

TL;DR: LC-MS/MS methods should undergo rigorous and systematic validation before introduction into patient care and can be controlled by sufficient LC separation-based sample workup before MS analysis.

TL;DR: HPLC-MS/MS has the potential to be further developed to a commonly applied high-throughput technique in clinical chemistry, complementary to present standard techniques as photometry and ligand binding methods.

TL;DR: Fifteen new stilbenoids including 11 phenylbenz ofurans, the stemofurans A-K, and four dihydrostilbenes, the stilbostemins A, C, E, and F were isolated and identified from a methanolic extract of Stemona collinsae roots.

TL;DR: The instrumentation matured significantly, the applications are well understood, and the in vitro diagnostics (IVD) industry is shaping the market by providing assay kits, certified instruments, andThe first laboratory automated LC-MS/MS instruments as an analytical core.