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Delphine Planas
Researcher at Pasteur Institute
Publications - 66
Citations - 4796
Delphine Planas is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Medicine & Antibody. The author has an hindex of 17, co-authored 44 publications receiving 1601 citations. Previous affiliations of Delphine Planas include University of Paris & Université de Montréal.
Papers
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Journal ArticleDOI
Estimated protection against COVID-19 based on predicted neutralisation titres from multiple antibody measurements in a longitudinal cohort, France, April 2020 to November 2021
Tom Woudenberg,Laurie Pinaud,Laura Tondeur,Stéphane Pelleau,A. de Thoisy,Françoise Donnadieu,Marija Backovic,Mickael Attia,Nathanaël Hozé,Cécile Duru,Aymar Davy Koffi,Sandrine Castelain,Marie-Noëlle Ungeheuer,Sandrine Fernandes Pellerin,Delphine Planas,Timothée Bruel,Simon Cauchemez,Olivier Schwartz,Arnaud Fontanet,Michael A. White +19 more
TL;DR: In this paper , the authors developed a method that predicts virus neutralization and disease protection based on variant-specific antibody measurements to SARS-CoV-2 antigens, and inferred protection estimates to symptomatic and severe COVID-19 using previously described relationships between neutralisation titres and protection estimates.
Posted ContentDOI
Antiviral activities of sotrovimab against BQ.1.1 and XBB.1.5 in sera of treated patients
Timothée Bruel,Françoise Porrot,Isabelle Staropoli,Delphine Planas,Florence Guivel-Benhassine,Julien Puech,Matthieu Prot,Sandie Munier,Cathia Soulié,Karen Zafilaza,Clovis Lusivika-Nzinga,Céline Dorival,Diana Molino,Hélène Péré,Youri Yordanov,Etienne Simon-Loriere,David Veyer,Fabrice Carrat,Olivier Schwartz,Anne-Geneviève Marcelin,Guillaume Martin-Blondel +20 more
TL;DR: In this article , the authors investigated neutralization and antibody-dependent cellular cytotoxicity (ADCC) of D614G, BQ.1 and XBB.1.5 in 320 sera from 80 immunocompromised patients.
Book ChapterDOI
Flow Cytometry Sorting of Memory CCR6+CD4+ T-Cells for HIV Reservoir Quantification.
TL;DR: A step-by-step flow cytometry-based protocol to isolate a fraction of Th17-enriched cells from PBMC based on their expression of the Th17 surface marker CCR6 allows subsequent PCR/RT-PCR-based HIV DNA/RNA quantifications, as well as their culture for quantitative viral outgrowth assays (QVOA).
Journal ArticleDOI
Complement-dependent mpox-virus-neutralizing antibodies in infected and vaccinated individuals
Mathieu Hubert,Florence Guivel-Benhassine,Timothée Bruel,Françoise Porrot,Delphine Planas,Jessica Vanhomwegen,Aurélie Wiedemann,Sonia Burrel,Stéphane Marot,Romain Palich,Gentiane Monsel,Sebastien Gallien,José-Luis López-Zaragoza,William Vindrios,Fabien Taieb,Sandrine Fernandes-Pellerin,Maurine Delhaye,Hélène Laude,Laurence Arowas,Marie-Noëlle Ungeheuer,Laurent Hocqueloux,Valérie Pourcher,Thierry Prazuck,Anne-Geneviève Marcelin,Jean-Daniel Lelièvre,Christophe Batéjat,Yves Levy,Jean-Claude Manuguerra,Olivier Schwartz +28 more
TL;DR: Wang et al. as mentioned in this paper used two assays to quantify neutralizing antibodies (NAbs) in sera from control, MPXV-infected, or MVA-vaccinated individuals.
Posted ContentDOI
Modelling the association between neutralizing antibody levels and SARS-CoV-2 viral dynamics : implications to define correlates of protection against infection
Guillaume Lingas,Delphine Planas,Hélène Péré,Darragh Duffy,Isabelle Staropoli,Françoise Porrot,Florence Guivel-Benhassine,Nicolas Chapuis,Camille Gobeaux,David Veyer,Constance Delaugerre,Jérôme Le Goff,P. Getten,Jérôme Hadjadj,A. Bellino,Bako Parfait,Jean-Marc Tréluyer,Olivier Schwartz,Jeremie Guedj,Sven A. Kerneis,Benjamin Terrier +20 more
TL;DR: In this paper , the authors analyzed the kinetics of both viral load and neutralizing antibody levels in a prospective cohort of individuals during acute infection by Alpha variant and showed that the progressive increase in neutralizing antibodies leads to a shortening of the half-life of both infected cells and infectious viral particles.