D
Denis O Shea
Researcher at Dublin Institute of Technology
Publications - 3
Citations - 273
Denis O Shea is an academic researcher from Dublin Institute of Technology. The author has contributed to research in topics: Phenanthroline & Denticity. The author has an hindex of 3, co-authored 3 publications receiving 256 citations.
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Journal ArticleDOI
Synthesis, X-ray crystal structures and biomimetic and anticancer activities of novel copper(II)benzoate complexes incorporating 2-(4'-thiazolyl)benzimidazole (thiabendazole), 2-(2-pyridyl)benzimidazole and 1,10-phenanthroline as chelating nitrogen donor ligands.
Michael Devereux,Denis O Shea,Andrew Kellett,Andrew Kellett,Malachy McCann,Maureen Walsh,Denise A. Egan,Carol Deegan,Kinga Kędziora,Georgina M. Rosair,Helge Müller-Bunz +10 more
TL;DR: The catalase and superoxide dismutase (SOD) activities of the four complexes along with those of the known phenanthroline complexes were investigated and the structural results for 4 represent a re-examination of this crystallographically known compound for which no hydrogen atom coordinates have been previously reported.
Journal ArticleDOI
Synthesis, antimicrobial activity and chemotherapeutic potential of inorganic derivatives of 2-(4'-thiazolyl)benzimidazole[thiabendazole]: X-ray crystal structures of [Cu(TBZH)2Cl]Cl.H2O.EtOH and TBZH2NO3 (TBZH=thiabendazole).
Michael Devereux,Malachy McCann,Denis O Shea,Rachel Kelly,Denise A. Egan,Carol Deegan,Kevin Kavanagh,Vickie McKee,Gregory J. Finn +8 more
TL;DR: The dimethyl sulphoxide soluble complexes 3 and 4, along with metal free TBZH were assessed for their cancer chemotherapeutic potential towards two human epithelial-derived cancer model cell lines and showed similar dose-dependent cytotoxicity in both cell lines.
Journal ArticleDOI
Synthesis and in vitro anti-microbial activity of manganese (II) complexes of 2,2-dimethylpentanedioic and 3,3-dimethylpentanedioic acid: X-ray crystal structure of [Mn(3dmepda)(phen)2] · 7.5H2O (3dmepdaH2=3,3-dimethylpentanedioic acid and phen=1,10-phenanthroline)
TL;DR: In this paper, the 2,2- and 3,3-dimethylpentanedioic acid (3dmepdaH2) were tested for their ability to inhibit the growth of Candida albicans.