D
Dennis B. Lubahn
Researcher at University of Missouri
Publications - 201
Citations - 29869
Dennis B. Lubahn is an academic researcher from University of Missouri. The author has contributed to research in topics: Estrogen receptor & Estrogen receptor alpha. The author has an hindex of 79, co-authored 200 publications receiving 28809 citations. Previous affiliations of Dennis B. Lubahn include Mayo Clinic & University of Missouri System.
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Journal ArticleDOI
Changes in nucleus accumbens gene expression accompany sex-specific suppression of spontaneous physical activity in aromatase knockout mice.
Dusti A. Shay,Rebecca J. Welly,Scott A. Givan,Nathan J. Bivens,Jill A. Kanaley,Brittney L. Marshall,Dennis B. Lubahn,Cheryl S. Rosenfeld,Victoria J. Vieira-Potter +8 more
TL;DR: It is suggested that whole body aromatase deletion would cause gene expression changes in the nucleus accumbens (NAc), a brain regulating motivated behaviors such as physical activity, which is suppressed with loss of estradiol, and this may result in reduced SPA and related metabolic abnormalities.
Journal ArticleDOI
Voluntary Wheel Running Partially Compensates for the Effects of Global Estrogen Receptor-α Knockout on Cortical Bone in Young Male Mice.
Rebecca K. Dirkes,Nathan C. Winn,Nathan C. Winn,Thomas J. Jurrissen,Dennis B. Lubahn,Victoria J. Vieira-Potter,Jaume Padilla,Pamela S. Hinton +7 more
TL;DR: In this paper, the main and interactive effects of ERKO and exercise on cortical geometry, trabecular micro-architecture, biomechanical strength, and sclerostin expression in male mice were explored.
Proceedings ArticleDOI
From gigabyte to kilobyte: a bioinformatics protocol for mining large RNA-Seq transcriptomics data
Jilong Li,Jie Hou,Lin Sun,Jordan Maximillian Wilkins,Yuan Lu,Chad E. Niederhuth,Benjamin Ryan Merideth,Thomas P. Mawhinney,Valeri V. Mossine,C. Michael Greenlief,John C. Walker,William R. Folk,Mark Hannink,Dennis B. Lubahn,James A. Birchler,Jianlin Cheng +15 more
TL;DR: RNAMiner was applied to datasets generated from Human, Mouse, Arabidopsis thaliana, and Drosophila melanogaster cells, and successfully identified differentially expressed genes, clustered them into cohesive functional groups, and constructed novel gene regulatory networks.
Journal ArticleDOI
Effects of nanosecond pulsed electric fields on the human prostate cancer cell line LNCaP
TL;DR: The 11betaHSD2 enzyme activity in LNCaP cells also decreased following exposure, thus supporting the initial hypothesis that ultrashort pulses affect intracellular structures; thus, a decrease in the enzyme activity could result in enhancing the anti-proliferative actions of glucocorticoids.
Journal ArticleDOI
Global estrogen receptor-α knockout has differential effects on cortical and cancellous bone in aged male mice
Rebecca K. Dirkes,Nathan C. Winn,Thomas J. Jurrissen,Dennis B. Lubahn,Victoria J. Vieira-Potter,Jaume Padilla,Pamela S. Hinton +6 more
TL;DR: Estrogen receptor-α knockout in female rodents results in bone loss associated with increased osteocyte sclerostin expression; whether this also occurs in males is unknown.