D
Dennis B. Lubahn
Researcher at University of Missouri
Publications - 201
Citations - 29869
Dennis B. Lubahn is an academic researcher from University of Missouri. The author has contributed to research in topics: Estrogen receptor & Estrogen receptor alpha. The author has an hindex of 79, co-authored 200 publications receiving 28809 citations. Previous affiliations of Dennis B. Lubahn include Mayo Clinic & University of Missouri System.
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Journal ArticleDOI
Estrogen action and male fertility: Roles of the sodium/hydrogen exchanger-3 and fluid reabsorption in reproductive tract function
Qing Zhou,Lane L. Clarke,Rong Nie,Kay Carnes,Li Wen Lai,Yeong Hau H. Lien,Alan S. Verkman,Dennis B. Lubahn,Jane S. Fisher,Benita S. Katzenellenbogen,Rex A. Hess +10 more
TL;DR: It is shown that estrogen regulates expression of the Na+/H+ exchanger-3 (NHE3) and the rate of 22Na+ transport, sensitive to an NHE3 inhibitor, and this raises the possibility of targeting ERα in developing a contraceptive for the male.
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Mechanism of Estrogen Action: Lessons from the Estrogen Receptor-α Knockout Mouse
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Common botanical compounds inhibit the hedgehog signaling pathway in prostate cancer.
Anna Slusarz,Nader S. Shenouda,Mary S. Sakla,Sara K. Drenkhahn,Acharan S. Narula,Ruth S. MacDonald,Cynthia Besch-Williford,Dennis B. Lubahn +7 more
TL;DR: These botanicals at pharmacologic concentrations are potentially safer and less expensive alternatives to cyclopamine and its pharmaceutical analogues for cancer therapy and are also able to reduce or delay prostate cancer in vivo in TRAMP mice.
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Evidence That Epithelial and Mesenchymal Estrogen Receptor-α Mediates Effects of Estrogen on Prostatic Epithelium
Gail P. Risbridger,Hong Wang,Peter Young,Takeshi Kurita,Y.Z. Wong,Dennis B. Lubahn,Gustafsson Ja,Gerald R. Cunha +7 more
TL;DR: A novel insight into the cell-cell interactions mediating estrogen action in the prostate via ERalpha is provided, indicating an essential role for ERalpha, but not ERbeta, in the induction of SQM of prostatic epithelium.
Journal Article
The Role of Estrogen Receptors and Androgen Receptors in Sex Steroid Regulation of B Lymphopoiesis
TL;DR: It is shown that estrogen-mediated inhibition of B cell precursor expansion in culture was blocked by a specific estrogen receptor antagonist (ICI 182,780), and stromal cells derived from ER alpha-targeted bone marrow were fully estrogen responsive.