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Diane C. Louie
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 31
Citations - 4180
Diane C. Louie is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Lymphoma & Gene rearrangement. The author has an hindex of 25, co-authored 31 publications receiving 4091 citations. Previous affiliations of Diane C. Louie include Columbia University.
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Journal ArticleDOI
BCL-6 protein is expressed in germinal-center B cells
Giorgio Cattoretti,Chih Chao Chang,Katarina Cechova,Jiandong Zhang,Bihui H. Ye,Brunangelo Falini,Diane C. Louie,Kenneth Offit,Raju S.K. Chaganti,Riccardo Dalla-Favera +9 more
TL;DR: The results indicate that the expression of the BCL-6 gene is specifically regulated during B-cell differentiation and suggest a role for B CL-6 in germinal center development or function.
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A 2-step comprehensive high-dose chemoradiotherapy second-line program for relapsed and refractory Hodgkin disease: analysis by intent to treat and development of a prognostic model
Craig H. Moskowitz,Stephen D. Nimer,Andrew D. Zelenetz,Tania Trippett,Eric Hedrick,Daniel A. Filippa,Diane C. Louie,Maria Gonzales,Janine Walits,Nancy Coady-Lyons,Jing Qin,Richard C. Frank,Joseph R. Bertino,Andre Goy,Ariela Noy,James P. O'Brien,David J. Straus,Carol S. Portlock,Joachim Yahalom +18 more
TL;DR: These results compare favorably with other series and document the feasibility and efficacy of giving uniform dose-dense and dose-intense cytoreductive chemotherapy and integrating accelerated fractionation radiotherapy into an ASCT treatment program.
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Rearrangement of the bcl-6 gene as a prognostic marker in diffuse large-cell lymphoma
Kenneth Offit,Francesco Lo Coco,Francesco Lo Coco,Diane C. Louie,Nasser Z. Parsa,Denis H. Y. Leung,Carol S. Portlock,Bihui H. Ye,Florigio Lista,Daniel A. Filippa,Ayala Rosenbaum,Marc Ladanyi,Suresh C. Jhanwar,Riccardo Dalla-Favera,R.S.K. Chaganti +14 more
TL;DR: Rearrangement of the bcl-6 gene correlated with a favorable clinical outcome in DLLC and may thus serve as a prognostic marker in patients with this form of malignant lymphoma.
Journal ArticleDOI
p53 mutations are associated with histologic transformation of follicular lymphoma
F. Lo Coco,Gianluca Gaidano,Diane C. Louie,Kenneth Offit,Raju S.K. Chaganti,Riccardo Dalla-Favera +5 more
TL;DR: Findings indicate that p53 mutations are associated with and may be responsible for histologic transformation of follicular lymphoma.
Journal ArticleDOI
Chromosomal and gene amplification in diffuse large B-cell lymphoma
Pulivarthi H. Rao,Jane Houldsworth,Katerina Dyomina,Nasser Z. Parsa,Juan C. Cigudosa,Diane C. Louie,Leslie Popplewell,Kenneth Offit,Suresh C. Jhanwar,R. S. K. Chaganti +9 more
TL;DR: Data show, for the first time, that amplification of chromosomal regions and genes is a frequent phenomenon in DLBL and demonstrates their potential significance in lymphomagenesis.