F
F. Lo Coco
Researcher at University of Turin
Publications - 47
Citations - 3756
F. Lo Coco is an academic researcher from University of Turin. The author has contributed to research in topics: Acute promyelocytic leukemia & Leukemia. The author has an hindex of 23, co-authored 47 publications receiving 3646 citations. Previous affiliations of F. Lo Coco include University of Milan & Columbia University.
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Journal ArticleDOI
Alterations of a Zinc Finger-Encoding Gene, BCL-6, in Diffuse Large-Cell Lymphoma
Bihui H. Ye,F. Lista,F. Lo Coco,Daniel M. Knowles,Kenneth Offit,R. S. K. Chaganti,Riccardo Dalla-Favera +6 more
TL;DR: A gene was cloned from chromosomal translocations affecting band 3q27 that codes for a 79-kilodalton protein that is homologous with zinc finger-transcription factors and may be a proto-oncogene specifically involved in the pathogenesis of diffuse large-cell lymphoma.
Journal ArticleDOI
Acute promyelocytic leukemia: from genetics to treatment.
Francesco Grignani,Marta Fagioli,Myriam Alcalay,Letizia Longo,P P Pandolfi,Emilio Donti,Andrea Biondi,F. Lo Coco,Pier Giuseppe Pelicci +8 more
Journal ArticleDOI
p53 mutations are associated with histologic transformation of follicular lymphoma
F. Lo Coco,Gianluca Gaidano,Diane C. Louie,Kenneth Offit,Raju S.K. Chaganti,Riccardo Dalla-Favera +5 more
TL;DR: Findings indicate that p53 mutations are associated with and may be responsible for histologic transformation of follicular lymphoma.
Journal ArticleDOI
Characterization of acute promyelocytic leukemia cases lacking the classic t(15;17): results of the European Working Party
David Grimwade,Andrea Biondi,M J Mozziconacci,Anne Hagemeijer,Roland Berger,M. Neat,Kathy Howe,Nicole Dastugue,Joop H. Jansen,Isabelle Radford-Weiss,F. Lo Coco,Michel Lessard,Jesús M. Hernández,Eric Delabesse,David R. Head,Vincenzo Liso,Danielle Sainty,G. Flandrin,Ellen Solomon,Françoise Birg,Marina Lafage-Pochitaloff +20 more
TL;DR: In this paper, the authors used morphologic, cytogenetic, and molecular analyses for optimal management of acute promyelocytic leukemia (APL) patients and better understanding of the pathogenesis of the disease.
Journal ArticleDOI
Rearrangements of the BCL6 gene in diffuse large cell non-Hodgkin's lymphoma
F. Lo Coco,Bihui H. Ye,F. Lista,Paolo Corradini,Kenneth Offit,Daniel M. Knowles,Raju S.K. Chaganti,Riccardo Dalla-Favera +7 more
TL;DR: BCL6 rearrangements represent the first genetic lesion specifically and recurrently associated with DLLC and should prove useful for understanding the pathogenesis as well as for the clinical monitoring of these tumors.