D
Didar Asik
Researcher at State University of New York System
Publications - 11
Citations - 142
Didar Asik is an academic researcher from State University of New York System. The author has contributed to research in topics: Standard hydrogen electrode & Paramagnetism. The author has an hindex of 5, co-authored 10 publications receiving 64 citations. Previous affiliations of Didar Asik include University at Buffalo.
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Journal ArticleDOI
A Class of Fe III Macrocyclic Complexes with Alcohol Donor Groups as Effective T 1 MRI Contrast Agents
Eric M. Snyder,Didar Asik,Samira M. Abozeid,Ariel Burgio,Gage Bateman,Steven G. Turowski,Joseph A. Spernyak,Janet R. Morrow +7 more
TL;DR: It is shown that one member of a new class of high spin macrocyclic Fe(III) complexes produces more intense contrast in mice kidneys and liver at 30 minutes post injection than does a commercially used Gd( III) agent and also produces similar T1 relaxivity in serum phantoms at 4.7 T and 37 oC.
Journal ArticleDOI
Modulating the Properties of Fe(III) Macrocyclic MRI Contrast Agents by Appending Sulfonate or Hydroxyl Groups.
Didar Asik,Rachel Smolinski,Samira M. Abozeid,Travis Mitchell,Steven G. Turowski,Joseph A. Spernyak,Janet R. Morrow +6 more
TL;DR: Rapid blood clearance and poor binding to serum albumin identify Fe(L1)(OH2) for development as an extracellular fluid contrast agent as well as previously studied analogues with benzyl groups.
Journal ArticleDOI
Binding and Release of FeIII Complexes from Glucan Particles for the Delivery of T1 MRI Contrast Agents.
Akanksha Patel,Didar Asik,Eric M. Snyder,Alexandra E. Dilillo,Paul J. Cullen,Janet R. Morrow +5 more
TL;DR: It is shown that the unique coordination chemistry of FeIII‐based macrocyclic T1 MRI contrast agents permits facile encapsulation in GPs, and GPs labeled with the simple FeIII complexes are stable under physiologically relevant conditions, despite the absence of amphiphilic groups.
Journal ArticleDOI
Dinuclear Fe(III) Hydroxypropyl-Appended Macrocyclic Complexes as MRI Probes.
TL;DR: In this paper, four high-spin Fe(III) macrocyclic complexes, including three dinuclear and one mononuclear complex, were prepared toward the development of more effective iron-based magnetic resonance imaging (MRI) contrast agents.
Journal ArticleDOI
MRI and fluorescence studies of Saccharomyces cerevisiae loaded with a bimodal Fe(III) T1 contrast agent
TL;DR: F fungi, specifically the budding yeast Saccharomyces cerevisiae, can be loaded with Fe(III) T1 contrast agents and are robust towards dissociation and produce moderate T1 effects, despite lacking inner-sphere water ligands.