D
Dirk Posthouwer
Researcher at Maastricht University Medical Centre
Publications - 48
Citations - 823
Dirk Posthouwer is an academic researcher from Maastricht University Medical Centre. The author has contributed to research in topics: Hepatitis C & Hepatitis C virus. The author has an hindex of 14, co-authored 44 publications receiving 680 citations. Previous affiliations of Dirk Posthouwer include Gelre Hospitals & Utrecht University.
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Journal ArticleDOI
Declining Hepatitis C Virus (HCV) Incidence in Dutch Human Immunodeficiency Virus-Positive Men Who Have Sex With Men After Unrestricted Access to HCV Therapy
Anne Boerekamps,Guido E.L. van den Berk,F. N. Lauw,Eliane M. S. Leyten,Marjo E. E. van Kasteren,Arne van Eeden,Dirk Posthouwer,Mark A. A. Claassen,Anton S M Dofferhoff,D. W. M. Verhagen,Wouter F W Bierman,Kamilla D. Lettinga,Frank P. Kroon,Corine E Delsing,Paul H. P. Groeneveld,Robert Soetekouw,Edgar J G Peters,Sebastiaan J. Hullegie,Stephanie Popping,David A. M. C. van de Vijver,Charles A. Boucher,Joop E. Arends,Bart J. A. Rijnders +22 more
TL;DR: Unrestricted DAA availability in the Netherlands was followed by a 51% decrease in acute HCV infections among HIV-positive MSM, which contradicts a decrease in risk behavior as an alternative explanation.
Journal ArticleDOI
Progression to end-stage liver disease in patients with inherited bleeding disorders and hepatitis C: an international, multicenter cohort study.
Dirk Posthouwer,Michael Makris,Thynn Thynn Yee,Krista Fischer,Joost J. van Veen,Anja Griffioen,Karel J. van Erpecum,Eveline P. Mauser-Bunschoten +7 more
TL;DR: With longer duration of HCV infection, the risk of developing ESLD is emerging in patients with inherited bleeding disorders and risk factors for rapid progression are alcohol abuse, coinfection with HIV, older age at infection, and presence ofHCV genotype 1.
Journal ArticleDOI
Hepatitis C and health-related quality of life among patients with hemophilia.
Dirk Posthouwer,Iris Plug,Johanna G. van der Bom,Krista Fischer,Frits R. Rosendaal,Eveline P. Mauser-Bunschoten +5 more
TL;DR: Hepatitis C infection was associated with a decrease of HRQoL on the domains of general health and vitality in patients with hemophilia, and Hemophilia patients infected with HCV scored lower on the HRZoL domains ofgeneral health and Vitality than hemophili patients who had never been infected withHCV.
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Long-term follow-up of hepatitis C infection in a large cohort of patients with inherited bleeding disorders
Dietje E. Fransen van de Putte,Michael Makris,Krista Fischer,Thynn Thynn Yee,Lisa Kirk,Karel J. van Erpecum,David Patch,Dirk Posthouwer,Dirk Posthouwer,Eveline P. Mauser-Bunschoten +9 more
TL;DR: After over 30 years of HCV infection, ESLD occurred in a significant proportion of patients with inherited bleeding disorders, and HCC appears to be an increasing problem.
Journal ArticleDOI
Influenza and pneumococcal vaccination as a model to assess C-reactive protein response to mild inflammation
TL;DR: The findings show that the influenza vaccine alone as well as the combination of the influenza and pneumococcal vaccine increases CRP-levels with a peak 2 days after vaccination.