Hepatitis C and health-related quality of life among patients with hemophilia.
Dirk Posthouwer,Iris Plug,Johanna G. van der Bom,Krista Fischer,Frits R. Rosendaal,Eveline P. Mauser-Bunschoten +5 more
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TLDR
Hepatitis C infection was associated with a decrease of HRQoL on the domains of general health and vitality in patients with hemophilia, and Hemophilia patients infected with HCV scored lower on the HRZoL domains ofgeneral health and Vitality than hemophili patients who had never been infected withHCV.Citations
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Extent of illicit drug use and dependence, and their contribution to the global burden of disease.
Louisa Degenhardt,Wayne Hall +1 more
TL;DR: The regional and global distribution of use and estimated health burden from illicit drugs is outlined, and the health-related harms of cannabis use differ from those of amphetamine, cocaine, and opioid use, in that cannabis contributes little to mortality.
Journal ArticleDOI
Co‐morbidity in the ageing haemophilia patient: the down side of increased life expectancy
TL;DR: It is reported that haemophilia seems to protect against cardiovascular disease, although the incidence is increasing, and co‐morbidity has a major psychological impact, and an important effect on quality of life.
Journal ArticleDOI
Co‐morbidities and quality of life in elderly persons with haemophilia
TL;DR: This review focuses on co‐morbidities in the ageing haemophilia patients, their impact on quality of life and their complex management.
Journal ArticleDOI
Social participation of patients with hemophilia in the Netherlands
I. Plug,Marjolein Peters,Eveline P. Mauser-Bunschoten,Arja de Goede-Bolder,L. Heijnen,Cees Smit,José Willemse,Frits R. Rosendaal,Johanna G. van der Bom,Johanna G. van der Bom +9 more
TL;DR: Despite major improvements in treatment during the last decades, patients with hemophilia are still less involved in full-time paid work and suffer more from occupational disability than men from the general population.
Journal ArticleDOI
Health-related quality of life among adult patients with moderate and severe von Willebrand disease
E. M. De Wee,Eveline P. Mauser-Bunschoten,J. G. van der Bom,M. Degenaar-Dujardin,H. C. J. Eikenboom,Karin Fijnvandraat,A. de Goede-Bolder,B. A. P. Laros-van Gorkom,Karina Meijer,H. Raat,Frank W.G. Leebeek +10 more
TL;DR: HR‐QoL is lower in VWD patients compared with the general population, and a more severe bleeding phenotype was associated with lower scores on the domains of physical functioning, role limitations due to physical function, bodily pain, general health, social functioning and physical component summary.
References
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The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection.
John E. Ware,Cathy D. Sherbourne +1 more
TL;DR: A 36-item short-form survey designed for use in clinical practice and research, health policy evaluations, and general population surveys to survey health status in the Medical Outcomes Study is constructed.
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The RAND-36 measure of health-related quality of life
Ron D. Hays,Leo S. Morales +1 more
TL;DR: This paper provides example applications of the RAND-36 cross-sectionally and longitudinally, provides information on what a clinically important difference is for the Rand-36 scales, and provides guidance for summarizing theRand-36 in a single number.
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Chronic hepatitis C virus infection causes a significant reduction in quality of life in the absence of cirrhosis
TL;DR: Patients with chronic HCV infection who had used intravenous drugs in the past had the greatest impairment in quality-of-life scores, but the reduction in quality of life scores was still found in patients who had never used drugs.
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Mortality from liver cancer and liver disease in haemophilic men and boys in UK given blood products contaminated with hepatitis C
Sarah C. Darby,D. W. Ewart,Paul L. F. Giangrande,R. J. D. Spooner,Charles R. Rizza,Geoffrey Dusheiko,Christine A. Lee,Christopher A. Ludlam,F. Eric Preston +8 more
TL;DR: There is an emerging risk of mortality from liver disease and liver cancer in the UK haemophilia population in individuals both infected and uninfected with HIV-1, which probably results from infection with hepatitis C.