D
Dominic Alibhai
Researcher at University of Bristol
Publications - 34
Citations - 1011
Dominic Alibhai is an academic researcher from University of Bristol. The author has contributed to research in topics: Fluorescence-lifetime imaging microscopy & Medicine. The author has an hindex of 12, co-authored 30 publications receiving 736 citations. Previous affiliations of Dominic Alibhai include King's College London & Imperial College London.
Papers
More filters
Journal ArticleDOI
Rapid Global Fitting of Large Fluorescence Lifetime Imaging Microscopy Datasets
Sean C. Warren,Anca Margineanu,Dominic Alibhai,Douglas J. Kelly,Clifford Talbot,Yuriy Alexandrov,Ian Munro,Matilda Katan,Christopher Dunsby,Paul M. W. French +9 more
TL;DR: This work presents a computationally efficient global analysis algorithm for the analysis of time-correlated single photon counting (TCSPC) or time-gated FLIM data based on variable projection, requiring less than a minute to analyse time series and multiwell plate datasets with hundreds of FLIM images on standard personal computers.
Journal ArticleDOI
A transient pool of nuclear F-actin at mitotic exit controls chromatin organization
Christian Baarlink,Matthias Plessner,Alice Sherrard,Kohtaro Morita,Shinji Misu,David Virant,Eva-Maria Kleinschnitz,Robert L. Harniman,Dominic Alibhai,Stefan Baumeister,Kei Miyamoto,Ulrike Endesfelder,Abderrahmane Kaidi,Robert Grosse +13 more
TL;DR: The transient formation of nuclear actin filaments (F-actin) during mitotic exit is described, identifying a cell-cycle-specific and spatiotemporally controlled form of nuclear F- actin that reorganizes the mammalian nucleus after mitosis.
Journal ArticleDOI
Engineered synthetic scaffolds for organizing proteins within the bacterial cytoplasm
Matthew J. Lee,Judith Mantell,Lorna Hodgson,Dominic Alibhai,Jordan M. Fletcher,Ian R. Brown,Stefanie Frank,Wei-Feng Xue,Paul Verkade,Derek N. Woolfson,Martin J. Warren +10 more
TL;DR: The enzymes pyruvate decarboxylase and alcohol dehydrogenase have been directed to the filaments, leading to enhanced ethanol production in these engineered bacterial cells compared to those that do not produce the scaffold.
Journal ArticleDOI
FLIM FRET Technology for Drug Discovery: Automated Multiwell-Plate High-Content Analysis, Multiplexed Readouts and Application in Situ
Sunil Kumar,Dominic Alibhai,Anca Margineanu,Romain F. Laine,Gordon T. Kennedy,J. McGinty,Sean C. Warren,Douglas J. Kelly,Yuriy Alexandrov,Ian Munro,Clifford Talbot,Daniel W. Stuckey,Christopher Kimberly,Bertrand Viellerobe,Francois Lacombe,Eric Lam,Harriet B. Taylor,Margaret J. Dallman,Gordon Stamp,Edward J. Murray,Frank Stuhmeier,Alessandro Sardini,Matilda Katan,Daniel S. Elson,Mark A. A. Neil,Christopher Dunsby,Paul M. W. French +26 more
TL;DR: An automated FLIM multiwell-plate reader is described for high content analysis of fixed and live cells, tomographic FLIM in zebrafish and FLIM FRET of live cells via confocal endomicroscopy and the potential for multiple simultaneous FLIM (FRET) readouts in microscopy is illustrated.
Journal ArticleDOI
Tailored self-assembled photocatalytic nanofibres for visible-light-driven hydrogen production.
Jia Tian,Jia Tian,Yifan Zhang,Yifan Zhang,Lili Du,Yunxiang He,Xu-Hui Jin,Samuel Pearce,Jean-Charles Eloi,Robert L. Harniman,Dominic Alibhai,Ruquan Ye,David Lee Phillips,Ian Manners,Ian Manners +14 more
TL;DR: A high-performance recyclable photocatalytic core–shell nanofibre system that integrates a cobalt catalyst and a photosensitizer in close proximity for hydrogen production from water using visible light is described.