D
Donald E. Low
Researcher at University of Toronto
Publications - 362
Citations - 25624
Donald E. Low is an academic researcher from University of Toronto. The author has contributed to research in topics: Population & Streptococcus pneumoniae. The author has an hindex of 88, co-authored 359 publications receiving 24384 citations. Previous affiliations of Donald E. Low include Trillium Health Centre & New York City Department of Health and Mental Hygiene.
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Journal ArticleDOI
Antimicrobial Drug Use and Resistance among Respiratory Pathogens in the Community
TL;DR: As the authors enter a new era in the use of fluoroquinolones for the treatment of respiratory tract infections, health care professionals have an opportunity to apply lessons learned in the past to minimize or prevent the development of resistance to this class of antimicrobial drugs in the future.
Journal ArticleDOI
Emergence of Macrolide Resistance in Throat Culture Isolates of Group A Streptococci in Ontario, Canada, in 2001
Kevin Katz,Allison McGeer,Allison McGeer,Carla Duncan,Aisha Ashi-Sulaiman,Barbara M. Willey,Alicia Sarabia,Jacquie McCann,Sylvia Pong-Porter,Yana Rzayev,Joyce C. S. de Azavedo,Joyce C. S. de Azavedo,Donald E. Low,Donald E. Low +13 more
TL;DR: Pulsed-field gel electrophoresis found that two clones, with patterns identical to those of serotypes M1 and M4, accounted for 19.4 and 68.1% of the macrolide-resistant isolates, respectively.
Book ChapterDOI
The Reemergence of Severe Group A Streptococcal Disease: an Evolutionary Perspective
TL;DR: The author believes that as population immunity increases one will once again return to periods of waxing and waning of group A streptococcal disease severity, which is most likely related to changes in serotype distribution, production of toxins, and/or other factors.
Journal ArticleDOI
New endemic Legionella pneumophila serogroup I clones, Ontario, Canada.
Nathalie Tijet,Patrick Tang,Mya Romilowych,Carla Duncan,Victoria Ng,David N. Fisman,Frances B. Jamieson,Donald E. Low,Cyril Guyard +8 more
TL;DR: Identifying geographic distribution can improve surveillance and clinical testing procedures and help identify patients at risk of infectious disease by identifying geographical distributions of infectious diseases.
Journal ArticleDOI
Plasmid comparison and molecular analysis of Klebsiella pneumoniae harbouring bla(KPC) from New York City and Toronto.
Laura F. Mataseje,David A. Boyd,Barbara M. Willey,N. Prayitno,Nathan Kreiswirth,A. Gelosia,Susan M. Poutanen,Donald E. Low,Donald E. Low,Stephen G. Jenkins,Kevin Katz,Michael R. Mulvey +11 more
TL;DR: The dissemination of bla(KPC) is due both to carriage of similar KPC-harbouring plasmids within genetically distinct K. pneumoniae and to clonal spread of K. infections with unrelated KPC plasmid mechanisms.