D
Donald E. Low
Researcher at University of Toronto
Publications - 362
Citations - 25624
Donald E. Low is an academic researcher from University of Toronto. The author has contributed to research in topics: Population & Streptococcus pneumoniae. The author has an hindex of 88, co-authored 359 publications receiving 24384 citations. Previous affiliations of Donald E. Low include Trillium Health Centre & New York City Department of Health and Mental Hygiene.
Papers
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Journal ArticleDOI
Prevalence and Characterization of Invasive Isolates of Streptococcus pyogenes with Reduced Susceptibility to Fluoroquinolones
Jeff Powis,Jeff Powis,Allison McGeer,Allison McGeer,Carla Duncan,Ryan Goren,Joyce C. S. de Azavedo,Joyce C. S. de Azavedo,Darrin J. Bast,Darrin J. Bast,Sylvia Pong-Porter,Tony Mazzulli,Tony Mazzulli,Karen Green,Barbara M. Willey,Donald E. Low,Donald E. Low +16 more
TL;DR: Fluoroquinolone susceptibility testing was performed on invasive group A streptococcus isolates from 1992-1993 and 2003 from Ontario, Canada, and none were nonsusceptible to levofloxacin.
Journal ArticleDOI
Neuraminidase-inhibitor resistance testing for pandemic influenza A (H1N1) 2009 in Ontario, Canada.
Jean Longtin,Samir N. Patel,Alireza Eshaghi,Ernesto Lombos,Rachel R. Higgins,David C. Alexander,Romy Olsha,John Doyle,Dat Tran,Alicia Sarabia,Christine H. Lee,Nathalie Bastien,Yan Li,Donald E. Low,Guy Boivin,Jonathan B. Gubbay +15 more
TL;DR: Oseltamivir resistance was not frequent during the 2009-2010 influenza season but was identified with a systematic and prospective approach to resistance testing and the suggested indications for antiviral susceptibility testing in Canada are reported.
Journal ArticleDOI
Integrated whole-genome sequencing and temporospatial analysis of a continuing Group A Streptococcus epidemic
Nahuel Fittipaldi,Gregory J. Tyrrell,Donald E. Low,Irene Martin,David Lin,Kumar L Hari,James M. Musser +6 more
TL;DR: It is discovered that emm59 GAS organisms are undergoing continued multiclonal evolutionary expansion, and previously identified geographic patterns of strain dissemination are being diluted as mixing of subclones over time and space occurs.
Journal ArticleDOI
Community-acquired antibiotic resistance in urinary isolates from adult women in Canada
TL;DR: TMP-SMX continues to be appropriate as first-line empirical treatment of acute cystitis in adult women in Canada, as resistance remains below 20%, however, TMP- SMX resistance is higher in older women and in some provinces.
Book ChapterDOI
Superantigenic Activity Produced by Group A Streptococcal Isolates is Neutralized by Plasma from IVIG-Treated Streptococcal Toxic Shock Snydrome Patients
TL;DR: Overproduction, or in vivo administration, of inflammatory cytokines has been shown to induce many of the symptoms associated with STSS including fever, hypotension, and multiorgan failure.