D
Donald E. Low
Researcher at University of Toronto
Publications - 362
Citations - 25624
Donald E. Low is an academic researcher from University of Toronto. The author has contributed to research in topics: Population & Streptococcus pneumoniae. The author has an hindex of 88, co-authored 359 publications receiving 24384 citations. Previous affiliations of Donald E. Low include Trillium Health Centre & New York City Department of Health and Mental Hygiene.
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Journal ArticleDOI
Clinical significance of untreated candida species isolated from ascites in cirrhotic patients
Anna Norrby-Teglund,Matthew P. Muller,Allison McGeer,Bing Siang Gan,Veena Guru,John M.A. Bohnen,Pontus Thulin,Donald E. Low +7 more
TL;DR: The study suggests that the use of a medical regimen including IVIG in patients with severe GAS soft tissue infections may allow an initial non-operative or minimally invasive approach, which can limit the need to perform immediate wide debridements and amputations in unstable patients.
Journal ArticleDOI
FOCUS 2: a randomized, double-blinded, multicentre, Phase III trial of the efficacy and safety of ceftaroline fosamil versus ceftriaxone in community-acquired pneumonia
Donald E. Low,Thomas M. File,Paul B. Eckburg,George H. Talbot,H. David Friedland,Jon Lee,Lily Llorens,Ian A. Critchley,Dirk Thye,Jorge Corral,Eduardo Giugno,Maria del Rosario Gonzalez Arzac,Diego Maurizi,Javier Altclas,Germán Ambasch,Abel Jasovich,Angel Ramon Minguez,María Eugenia Oliva,Osvaldo Teglia,Carlos E. Bergallo,Maria Antonia Mastruzzo,Graciana Isabel Morera,Pabio Gustavo Scapellato,Ricardo Lamberghini,Analia Mykietiuk,Christian G. Remolif,Manuel Jose Barros Monge,Maria Isabel Enriqueta Campos Barker,Sara Mireya Chernilo Steinmann,Pablo Antonio Gaete Gutierrez,Sylvia Susana Muñoz Vejar,Mario Andres Calvo Arellano,Carolina Eugenia Chahin Anania,Arturo Jauregui Cruz,Gerardo Amaya Tapia,Moises Acuna Kaldman,Eduardo Noriega,Eduardo Demetrio Matos Prado,Carlos Ramos,Irina Andreeva,Rashad Abyshev,Yuri A. Antonovsky,Marina Balyuzek,Alla L. Esina,Alexander Gorelov,Oleg A. Khrustalev,Roman S. Kozlov,Vladislav Novozhenok,Veronika B. Popova,Svetlana Sobchenko,Vasily Trofimov,Sergey Yakovlev,Konstantin Zhidkov,Luminta Gabriela Ambert,Carmen Georgeta Fierbinteau,Valentina Ionescu,Mihai Marius Muresan,Cristina Mihaela Tanaseanu,Ognian Georgiev,Valdimir Hodzhev,Rosen Marinov,Hristo Metev,Marinka Peneva,Dimitar Popov,Milkana Simeonova,Ivars Krastins,Viktors Lovcinovsk,Viesturs Silins,Vita Svarcberga,Joachim Bargon,Thorsten Bauer,Rolf Bergmann,F.J. Meyer,Thomas Mueller,Tobias Welte,Sven Glaeser,Peter Hammerl,Hartmut Kern,Stefan Krueger,Peter Kujath,Achim Lies,Tom Schaberg,Oliver Schmalz,Wolfgang Schütte,Ryszarda Chazan,Dorota Górecka,Barbara Rogala,Adam Antczak,Tomasz Grodzicki,Karina Jahnz—Rö,Janusz Milanowski,Piotr Nalepa,Malgorzata Wróbel-Rajzer,Hanna Szelerska-Twardosz,Iwona Grzelewska—Rzymowska,Tomasz Kachel,Andrzej Marciniak,Bernard Panaszek,Andrzej Szczeklik,Jerzy Kozielski,Rafal Harat,Dariusz Jastrzebsk,Jacek Juszczak,Violetta Labij,Norbert Vetter,Josef Bolitschek,Josef Eckmayr,Sándor Molnár,Zsolt Pápai-Székely,Janos Szegedi,Ilona Vinkler,Mykhaylo Borscchivskyy,Oleksandr Dziublyk,Georgiy V. Dzyak,Oleg Kraydaschenko,Yuriy M. Mostovoy,Iurii S. Rudyk,V O Sushko,Vadim Vizir,Amal Kumar Bhattacharya,Mahabala Chakrapan,George D'Souza,G.S. Malpani,Parthiv Mehta,K.N. Mohar Rao,Deepak Talwar +125 more
TL;DR: Ceftaroline fosamil was well tolerated, with a safety profile that is similar to that of ceftriaxone and other cephalosporins, and is a promising agent for the treatment of CAP.
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Proton Pump Inhibitors and Hospitalization for Clostridium Difficile—Associated Disease: A Population-Based Study
TL;DR: Among community-dwelling older patients, PPI use is not a risk factor for hospitalization with CDAD, and there is no association between hospitalization for CDAD and more remote use of PPIs.
Journal ArticleDOI
Fatal Severe Acute Respiratory Syndrome Is Associated with Multiorgan Involvement by Coronavirus
Gabriella A. Farcas,Susan M. Poutanen,Susan M. Poutanen,Tony Mazzulli,Barbara M. Willey,Jagdish Butany,Sylvia L. Asa,Peter Faure,Poolak Akhavan,Donald E. Low,Kevin C. Kain +10 more
TL;DR: Fatal SARS was associated with multiorgan viral dissemination in a distribution that has implications for disease manifestation, viral shedding, and transmission.
Journal ArticleDOI
Viable Group A Streptococci in Macrophages during Acute Soft Tissue Infection
Pontus Thulin,Linda Johansson,Donald E. Low,Bing Siang Gan,Malak Kotb,Allison McGeer,Anna Norrby-Teglund +6 more
TL;DR: This is the first study to demonstrate that GAS survive intracellularly in macrophages during acute invasive infections, and the finding that high bacterial load is present even in tissue collected after prolonged intravenous antibiotic therapy is highlighted.