D
Dong Wang
Researcher at University of Nebraska Medical Center
Publications - 91
Citations - 4508
Dong Wang is an academic researcher from University of Nebraska Medical Center. The author has contributed to research in topics: Arthritis & Inflammation. The author has an hindex of 36, co-authored 88 publications receiving 4007 citations. Previous affiliations of Dong Wang include Eppley Institute for Research in Cancer and Allied Diseases & Peking University.
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Click Chemistry, A Powerful Tool for Pharmaceutical Sciences
TL;DR: Important aspects of the Huisgen cycloaddition will be reviewed, along with some of its many pharmaceutical applications, including bioconjugation, nanoparticle surface modification, and pharmaceutical-related polymer chemistry will all be covered.
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Bone-targeting macromolecular therapeutics.
TL;DR: Bone-targeting drug delivery systems based on water-soluble polymers can specifically direct candidate drugs to bone thereby reducing side effects due to non-specific tissue interactions.
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The Development of Novel Therapies for Rheumatoid Arthritis.
TL;DR: During the past 20 years, most of the development of new therapies in antirheumatic therapies is in DMARDs, especially biologicalDMARDs.
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Synthesis and evaluation of water-soluble polymeric bone-targeted drug delivery systems
TL;DR: Four polymeric bone-targeting conjugates were synthesized based on poly(ethylene glycol) (PEG) and poly[N-(2-hydroxypropyl)methacrylamide] (PHPMA) and indicated that these novel delivery systems could specifically accumulate in the bone tissue.
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Development of macromolecular prodrug for rheumatoid arthritis.
TL;DR: This manuscript provides a comprehensive overview of the rational design and optimization of macromolecular prodrugs for treatment of RA and illustrates the potential benefits of applying this therapeutic strategy to the treatment of other inflammatory diseases.