J
Jindřich Kopeček
Researcher at University of Utah
Publications - 347
Citations - 21116
Jindřich Kopeček is an academic researcher from University of Utah. The author has contributed to research in topics: Methacrylamide & N-(2-Hydroxypropyl) methacrylamide. The author has an hindex of 76, co-authored 343 publications receiving 19913 citations. Previous affiliations of Jindřich Kopeček include Icahn School of Medicine at Mount Sinai & Czechoslovak Academy of Sciences.
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Journal ArticleDOI
Diverse Applications of Nanomedicine
Beatriz Pelaz,Christoph Alexiou,Ramon A. Alvarez-Puebla,Frauke Alves,Frauke Alves,Anne M. Andrews,Sumaira Ashraf,Lajos P. Balogh,Laura Ballerini,Alessandra Bestetti,Cornelia Brendel,Susanna Bosi,Mónica Carril,Warren C. W. Chan,Chunying Chen,Xiaodong Chen,Xiaoyuan Chen,Zhen Cheng,Daxiang Cui,Jianzhong Du,Christian Dullin,Alberto Escudero,Alberto Escudero,Neus Feliu,Mingyuan Gao,Michael D. George,Yury Gogotsi,Arnold Grünweller,Zhongwei Gu,Naomi J. Halas,Norbert Hampp,Roland K. Hartmann,Mark C. Hersam,Patrick Hunziker,Ji Jian,Xingyu Jiang,Philipp Jungebluth,Pranav Kadhiresan,Kazunori Kataoka,Ali Khademhosseini,Jindřich Kopeček,Nicholas A. Kotov,Harald F. Krug,Dong Soo Lee,Claus-Michael Lehr,Kam W. Leong,Xing-Jie Liang,Mei Ling Lim,Luis M. Liz-Marzán,Xiaowei Ma,Paolo Macchiarini,Huan Meng,Helmuth Möhwald,Paul Mulvaney,Andre E. Nel,Shuming Nie,Peter Nordlander,Teruo Okano,Jose Oliveira,Tai Hyun Park,Reginald M. Penner,Maurizio Prato,Maurizio Prato,Víctor F. Puntes,Vincent M. Rotello,Amila Samarakoon,Raymond E. Schaak,Youqing Shen,Sebastian Sjöqvist,Andre G. Skirtach,Andre G. Skirtach,Mahmoud Soliman,Molly M. Stevens,Hsing-Wen Sung,Ben Zhong Tang,Rainer Tietze,Buddhisha Udugama,J. Scott VanEpps,Tanja Weil,Tanja Weil,Paul S. Weiss,Itamar Willner,Yuzhou Wu,Yuzhou Wu,Lily Yang,Zhao Yue,Qian Zhang,Qiang Zhang,Xian-En Zhang,Yuliang Zhao,Xin Zhou,Wolfgang J. Parak +91 more
TL;DR: An overview of recent developments in nanomedicine is provided and the current challenges and upcoming opportunities for the field are highlighted and translation to the clinic is highlighted.
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Hydrogel biomaterials: A smart future?
TL;DR: The application potential of synthetic, protein based, DNA based, and hybrid hydrogels bodes well for the future of this class of biomaterials.
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HPMA copolymer-anticancer drug conjugates: design, activity, and mechanism of action.
TL;DR: The data obtained indicated that macromolecular therapeutics activated different signaling pathways and possessed a different mechanism of action than free drugs, which bodes well for the success of future research aimed at identification of new intracellular molecular targets.
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Hybrid hydrogels assembled from synthetic polymers and coiled-coil protein domains
TL;DR: It is shown that well-characterized water-soluble synthetic polymers can be combined with well-defined folding motifs of proteins in hydrogels with engineered volume-change properties, as well as a hybrid hydrogel system assembled from water- soluble syntheticpolymers and a well- defined protein-folding motif, the coiled coil.
Journal ArticleDOI
HPMA copolymers: origins, early developments, present, and future.
Jindřich Kopeček,Pavla Kopečková +1 more
TL;DR: The overview covers the discovery of N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers, initial studies on their synthesis, evaluation of biological properties, and explorations of their potential as carriers of biologically active compounds in general and anticancer drugs in particular.