D
Doreen Muth
Researcher at Charité
Publications - 36
Citations - 8410
Doreen Muth is an academic researcher from Charité. The author has contributed to research in topics: Coronavirus & Middle East respiratory syndrome coronavirus. The author has an hindex of 27, co-authored 36 publications receiving 6988 citations. Previous affiliations of Doreen Muth include Bernhard Nocht Institute for Tropical Medicine & University of Bonn.
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Journal ArticleDOI
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
V. Stalin Raj,Huihui Mou,Saskia L. Smits,Dick H. W. Dekkers,Marcel A. Müller,Ronald Dijkman,Doreen Muth,Jeroen Demmers,Ali Moh Zaki,Ron A. M. Fouchier,Volker Thiel,Volker Thiel,Christian Drosten,Peter J. M. Rottier,Albert D. M. E. Osterhaus,Berend Jan Bosch,Bart L. Haagmans +16 more
TL;DR: Dipeptidyl peptidase 4 (DPP4; also known as CD26) is identified as a functional receptor for hCoV-EMC and will contribute critically to the understanding of the pathogenesis and epidemiology of this emerging human coronavirus, and may facilitate the development of intervention strategies.
Book ChapterDOI
Hosts and Sources of Endemic Human Coronaviruses.
TL;DR: New data suggest that HCoV-229E may actually be transferred from dromedary camels similar to Middle East respiratory syndrome (MERS) coronavirus, which provides important ecological parallels to the present prepandemic pattern of host associations of the MERS coronav virus.
Journal ArticleDOI
Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study
Chantal B.E.M. Reusken,Bart L. Haagmans,Marcel A. Müller,Carlos Gutierrez,Gert Jan Godeke,Benjamin Meyer,Doreen Muth,V. Stalin Raj,Laura Smits De Vries,Victor M. Corman,Jan Felix Drexler,Saskia L. Smits,Yasmin El Tahir,Rita de Sousa,Janko van Beek,Norbert Nowotny,Norbert Nowotny,Kees van Maanen,Ezequiel Hidalgo-Hermoso,Berend Jan Bosch,Peter J. M. Rottier,Albert D. M. E. Osterhaus,Christian Gortázar-Schmidt,Christian Drosten,Marion Koopmans +24 more
TL;DR: Both titres and seroprevalences in sera from different locations in Oman suggest widespread infection of camel populations, and possible animal reservoirs of MERS-CoV are investigated by assessing specific serum antibodies in livestock.
Journal ArticleDOI
Detection of a novel human coronavirus by real-time reverse-transcription polymerase chain reaction
Victor M. Corman,Isabella Eckerle,Tobias Bleicker,Ali Moh Zaki,Olfert Landt,Monika Eschbach-Bludau,S. van Boheemen,Robin Gopal,M Ballhause,Theo M. Bestebroer,Doreen Muth,Marcel A. Müller,Jan Felix Drexler,Maria Zambon,A.D.M.E. Osterhaus,R M Fouchier,Christian Drosten +16 more
TL;DR: Two real-time reverse-transcription polymerase chain reaction assays for a novel human coronavirus, targeting regions upstream of the E gene (upE) or within open reading frame (ORF)1b, respectively, observed no cross-reactivity with coronaviruses OC43, NL63, 229E, SARS-CoV or with 92 clinical specimens containing common human respiratory viruses.
Journal ArticleDOI
Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection
Christian Drosten,M Seilmaier,Victor M. Corman,W. J. Hartmann,Gregor Scheible,Stefan Sack,Wolfgang Guggemos,René Kallies,Doreen Muth,Sandra Junglen,Marcel A. Müller,Walter Haas,Hana Guberina,Tim Röhnisch,Monika Schmid-Wendtner,Souhaib Aldabbagh,Ulf Dittmer,Hermann Gold,Petra Graf,Frank Bonin,Andrew Rambaut,Andrew Rambaut,Clemens M. Wendtner +22 more
TL;DR: The first complete viral load profile in a case of MERS-CoV infection is provided, which might have shedding patterns that are different from those of severe acute respiratory syndrome and so might need alternative diagnostic approaches.