D
Dorothee Stichweh
Researcher at Baylor University
Publications - 8
Citations - 1166
Dorothee Stichweh is an academic researcher from Baylor University. The author has contributed to research in topics: Lupus erythematosus & Arthritis. The author has an hindex of 5, co-authored 8 publications receiving 1078 citations. Previous affiliations of Dorothee Stichweh include University of Texas Southwestern Medical Center & Baylor University Medical Center.
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Journal ArticleDOI
A Modular Analysis Framework for Blood Genomics Studies: Application to Systemic Lupus Erythematosus
Damien Chaussabel,Charles T. Quinn,Jing Shen,Pinakeen Patel,Casey Glaser,Nicole Baldwin,Dorothee Stichweh,Derek Blankenship,Lei Li,Indira Munagala,Lynda Bennett,Florence Allantaz,Asuncion Mejias,Monica I. Ardura,Ellen Kaizer,Laurence Monnet,Windy Allman,Henry B. Randall,Diane Johnson,Aimee Lanier,Marilynn Punaro,Knut M. Wittkowski,Perrin C. White,Joseph W. Fay,Goran B. Klintmalm,Octavio Ramilo,A. Karolina Palucka,Jacques Banchereau,Virginia Pascual +28 more
TL;DR: This work designed a strategy for microarray analysis that is based on the identification of transcriptional modules formed by genes coordinately expressed in multiple disease data sets that provide a stable framework for the visualization and functional interpretation of microarray data.
Journal ArticleDOI
Blood leukocyte microarrays to diagnose systemic onset juvenile idiopathic arthritis and follow the response to IL-1 blockade
Florence Allantaz,Damien Chaussabel,Dorothee Stichweh,Lynda Bennett,Windy Allman,Asuncion Mejias,Monica I. Ardura,Wendy K. Chung,Elisabeth Smith,Carol Wise,Karolina Palucka,Octavio Ramilo,Marilynn Punaro,Jacques Banchereau,Virginia Pascual +14 more
TL;DR: Leukocyte transcriptional signatures can be used to distinguish SoJIA from other febrile illnesses and to assess response to therapy and availability of early diagnostic markers may allow prompt initiation of therapy and prevention of disabilities.
Journal ArticleDOI
Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors.
Brun Mietzner,Makoto Tsuiji,Johannes F. Scheid,Klara Velinzon,Thomas Tiller,Klaus Abraham,Jose B. Gonzalez,Virginia Pascual,Dorothee Stichweh,Hedda Wardemann,Michel C. Nussenzweig +10 more
TL;DR: Heterogeneity in the frequency of memory B cells expressing SLE-associated autoantibodies suggests that this variable may be important in the outcome of therapies that ablate this compartment.
Journal ArticleDOI
Update on pediatric systemic lupus erythematosus.
TL;DR: An important role for interferon-alpha (IFN-α) in the pathogenesis of this disease and an overall striking homogeneity of leukocyte gene expression profiles in children and adults with SLE are indicated.
Journal ArticleDOI
Infantile Onset Panniculitis with Uveitis and Systemic Granulomatosis: A New Clinicopathologic Entity
Carine Wouters,Tammy M. Martin,Dorothee Stichweh,Marilynn Punaro,T. M. Doyle,Jinnell A. Lewis,Pierre Quartier,Carlos D. Rose +7 more
TL;DR: This report reports on 4 children with infantile-onset lobular panniculitis, high fever, uveitis, and systemic granulomatous inflammation recruited through the International Registry of Pediatric GranulOMatous Arthritis, where neither CARD15 nor CIAS1 mutations were found.