D
Douwe van Sinderen
Researcher at University College Cork
Publications - 502
Citations - 36731
Douwe van Sinderen is an academic researcher from University College Cork. The author has contributed to research in topics: Bifidobacterium breve & Bifidobacterium. The author has an hindex of 85, co-authored 456 publications receiving 30073 citations. Previous affiliations of Douwe van Sinderen include North Carolina State University & University of Groningen.
Papers
More filters
Journal ArticleDOI
Gut microbiota composition correlates with diet and health in the elderly
Marcus J. Claesson,Ian B. Jeffery,Susana Conde,Susan E. Power,Eibhlís M. O'Connor,Siobhán Cusack,Hugh M. B. Harris,M. Coakley,Bhuvaneswari Lakshminarayanan,Orla O'Sullivan,Gerald F. Fitzgerald,Jennifer Deane,Michael O'Connor,Norma Harnedy,Kieran O'Connor,Denis O'Mahony,Denis O'Mahony,Douwe van Sinderen,Martina Wallace,Lorraine Brennan,Catherine Stanton,Catherine Stanton,Julian R. Marchesi,Anthony P. Fitzgerald,Fergus Shanahan,Colin Hill,R. Paul Ross,R. Paul Ross,Paul W. O'Toole +28 more
TL;DR: The data support a relationship between diet, microbiota and health status, and indicate a role for diet-driven microbiota alterations in varying rates of health decline upon ageing.
Journal ArticleDOI
Composition, variability, and temporal stability of the intestinal microbiota of the elderly
Marcus J. Claesson,Siobhán Cusack,Orla O'Sullivan,Rachel Greene-Diniz,Heleen de Weerd,E. Flannery,Julian R. Marchesi,Julian R. Marchesi,Daniel Falush,Timothy G. Dinan,Gerald F. Fitzgerald,Catherine Stanton,Catherine Stanton,Douwe van Sinderen,Michael O'Connor,Norma Harnedy,Kieran O'Connor,Colm Henry,Denis O'Mahony,Denis O'Mahony,Anthony P. Fitzgerald,Fergus Shanahan,C. Twomey,C. Twomey,Colin Hill,R. Paul Ross,R. Paul Ross,Paul W. O'Toole +27 more
TL;DR: It is concluded that the fecal microbiota of the elderly shows temporal stability over limited time in the majority of subjects but is characterized by unusual phylum proportions and extreme variability.
Journal ArticleDOI
Genomics of Actinobacteria: Tracing the Evolutionary History of an Ancient Phylum
Marco Ventura,Carlos Canchaya,Andreas Tauch,Govind Chandra,Gerald F. Fitzgerald,Keith F. Chater,Douwe van Sinderen +6 more
TL;DR: An account of the recent explosion of actinobacterial genomics data is provided and an attempt to place this in a biological and evolutionary context.
Journal ArticleDOI
Bacteria as vitamin suppliers to their host: a gut microbiota perspective.
Jean Guy LeBlanc,Christian Milani,Graciela Savoy de Giori,Graciela Savoy de Giori,Fernando Sesma,Douwe van Sinderen,Marco Ventura +6 more
TL;DR: In this review, fermented foods with elevated levels of B-group vitamins produced by LAB used as starter cultures will be covered and genetic abilities for vitamin biosynthesis by selected human gut commensals will be discussed.
Journal ArticleDOI
The First Microbial Colonizers of the Human Gut: Composition, Activities, and Health Implications of the Infant Gut Microbiota
Christian Milani,Sabrina Duranti,Francesca Bottacini,Eoghan Casey,Francesca Turroni,Jennifer Mahony,Clara Belzer,Susana Delgado Palacio,Silvia Arboleya Montes,Leonardo Mancabelli,Gabriele Andrea Lugli,Juan M. Rodríguez,Lars Bode,Willem M. de Vos,Willem M. de Vos,Miguel Gueimonde,Abelardo Margolles,Douwe van Sinderen,Marco Ventura +18 more
TL;DR: The infant microbiota, the mechanisms that drive its establishment and composition, and how microbial consortia may be molded by natural or artificial interventions are described and the relevance of key microbial players of the infant gut microbiota, in particular bifidobacteria, with respect to their role in health and disease are discussed.