Dvir Netanely

TL;DR: This work transformed protein structures into residue interaction graphs (RIGs), where amino acid residues are graph nodes and their interactions with each other are the graph edges, and found that active site, ligand-binding and evolutionary conserved residues, typically have high closeness values.

TL;DR: The MITF/miR-211 axis that inhibits the invasive program by blocking adhesion is defined and NUAK1 is identified as a potential target for the treatment of metastatic melanoma.

TL;DR: It is shown that functional cell-mediated immunity is required for the maintenance of hippocampus-dependent spatial memory and that homeostatic-driven proliferation of lymphocytes, which expands the existing T cell repertoire, restored spatial memory deficits in aged mice.

TL;DR: The analysis of molecular classification of breast tumors using both expression and methylation data obtained from The Cancer Genome Atlas provides two prognostic gene sets that dissect and explain tumor variability within the luminal-A subgroup, thus, contributing to the advancement of subtype-specific diagnosis and treatment.

TL;DR: Evaluation of human mesenchymal stem cells showed significant decreases in osteogenic and chondrogenic gene expression and an increase in adipogenic gene expression, indicating that ex vivo adipose tissue engineering may benefit from simulated microgravity.